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身体体型对腹膜外腹腔镜前列腺癌根治术手术难度的影响

Impact of Body Habitus on Operative Difficulties during Extraperitoneal Laparoscopic Radical Prostatectomy.

作者信息

Weimin Yu, Haga Nobuhiro, Yanagida Tomohiko, Kurita Noriaki, Akihata Hidenori, Kojima Yoshiyuki

机构信息

Department of Urology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Department of Innovative Research and Education for Clinicians and Trainees (DiRECT), Fukushima Medical University Hospital, Fukushima, Japan.

出版信息

Urol J. 2016 Mar 5;13(1):2519-26.

PMID:26945656
Abstract

PURPOSE

The aim of the present study was to investigate whether patients' body habitus affects the operative difficulties associated with extraperitoneal laparoscopic radical prostatectomy (LRP). Therefore, the associations between body habitus and perioperative outcomes of surgery, including bleeding, operative time, and resection margins, were evaluated.

MATERIALS AND METHODS

Between August 2010 and July 2012, 40 consecutive patients with preoperative magnetic resonance imaging and abdominal X-ray examinations underwent extraperitoneal LRP for localized prostate cancer at our institution. The associations between anthropometric measurements and demographics of patients, operation duration, estimated blood loss (EBL), and resection margins were analyzed retrospectively. Multivariate analyses were performed, and P < .05 was considered significant.

RESULTS

On multiple regression analysis, the view of the prostatic apex (VPA) was significantly associated with EBL (P = .02), and body mass index (BMI) was significantly associated with operative time (P = .02). On multiple logistic regression analysis, protrusion of the prostate into the bladder was significantly associated with positive resection margins (P = .04).

CONCLUSION

The findings of the present study suggest that poor VPA, protrusion of the prostate into the bladder, and high BMI were related to operative difficulties in extraperitoneal LRP. If operative difficulty is predicted preoperatively, it would be better to prepare blood for transfusion and/or special instruments (e.g. flexible scope), or switch to other therapeutic procedures.

摘要

目的

本研究旨在调查患者的身体形态是否会影响腹膜外腹腔镜根治性前列腺切除术(LRP)相关的手术难度。因此,评估了身体形态与手术围手术期结果之间的关联,包括出血、手术时间和切缘情况。

材料与方法

2010年8月至2012年7月期间,在我们机构对40例术前行磁共振成像和腹部X线检查的患者进行了腹膜外LRP治疗局限性前列腺癌。回顾性分析了患者的人体测量数据与人口统计学特征、手术持续时间、估计失血量(EBL)和切缘之间的关联。进行了多变量分析,P < 0.05被认为具有统计学意义。

结果

多元回归分析显示,前列腺尖部视野(VPA)与EBL显著相关(P = 0.02),体重指数(BMI)与手术时间显著相关(P = 0.02)。多因素逻辑回归分析显示,前列腺突入膀胱与切缘阳性显著相关(P = 0.04)。

结论

本研究结果表明,VPA不佳、前列腺突入膀胱和高BMI与腹膜外LRP的手术难度相关。如果术前预测到手术难度,最好准备输血用血和/或特殊器械(如软性内镜),或改用其他治疗方法。

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The association between the outcomes of extraperitoneal laparoscopic radical prostatectomy and the anthropometric measurements of the prostate by magnetic resonance imaging.经磁共振成像测量前列腺人体测量学指标与腹膜外腹腔镜根治性前列腺切除术疗效的相关性。
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