Janssen A H J, Mommers E H H, Notter J, de Vries Reilingh T S, Wegdam J A
Department of Surgery, Elkerliek Hospital, Helmond, The Netherlands.
Department of Community Health, Birmingham City University, Birmingham, UK.
J Wound Care. 2016 Mar;25(3):154, 156-9. doi: 10.12968/jowc.2016.25.3.154.
Negative pressure wound therapy (NPWT) is a widely accepted treatment modality for open or infected wounds. Premature ending of NPWT occasionally occurs due to negative effects on the quality of life (QoL), however, the actual impact on QoL is unknown. The aim of this review is to analyse the effect of NPWT versus standard wound care (SWC) on QoL when used for the treatment of open or infected wounds.
A systematic literature search in a range of databases (PubMed, CINAHL, Medline, Web of Science, Science Direct Freedom Collection, SwetsWise, PSYCArticles and Infrotrac Custom Journals) using the following search terms; 'standard wound care', 'wound dressing', 'dressing', 'treatment', OR 'negative pressure wound therapy [MESH]', OR 'vacuum assisted closure' AND 'quality of life [MESH]', 'patient-satisfaction', OR 'experiences' was performed. Methodological quality was assessed using the methodological index for non-randomised studies (MINORS) checklist.
There were 42 studies identified, five matched the inclusion criteria: two randomised clinical trials (RCTs), one clinical comparative study, one exploratory prospective cohort study and one quasi experimental pilot study. Median MINORS-score was 75% (58%-96%). There were seven different questionnaires used to measure QoL or a subsidiary outcome. QoL in the NPWT group was lower in the first week, though no difference in QoL was observed thereafter.
This systematic review observed that QoL improved at the end of therapy independent of which therapy was used. NPWT led to a lower QoL during the first week of treatment, possible due to aniexty, after which a similar or better QoL was reported when compared with SWC. It could be suggested that NPWT might be associated with increased anxiety.
All authors of this publication have received no financial support or have personal interests conflicting with the objectivity of this manuscript.
负压伤口治疗（NPWT）是一种被广泛认可的开放性或感染性伤口治疗方式。然而，由于对生活质量（QoL）产生负面影响，NPWT有时会过早结束，但其对生活质量的实际影响尚不清楚。本综述旨在分析NPWT与标准伤口护理（SWC）用于治疗开放性或感染性伤口时对生活质量的影响。
在一系列数据库（PubMed、CINAHL、Medline、Web of Science、Science Direct Freedom Collection、SwetsWise、PSYCArticles和Infrotrac Custom Journals）中进行系统的文献检索，使用以下检索词：“标准伤口护理”、“伤口敷料”、“敷料”、“治疗”或“负压伤口治疗[医学主题词]”、或“真空辅助闭合”以及“生活质量[医学主题词]”、“患者满意度”或“体验”。使用非随机研究的方法学指标（MINORS）清单评估方法学质量。
共识别出42项研究，5项符合纳入标准：2项随机临床试验（RCT）、1项临床对比研究、1项探索性前瞻性队列研究和1项准实验性试点研究。MINORS评分中位数为75%（58%-96%）。使用了7种不同的问卷来测量生活质量或次要结局。NPWT组在第一周的生活质量较低，但此后未观察到生活质量的差异。
本系统综述观察到，无论使用哪种治疗方法，治疗结束时生活质量均有所改善。NPWT在治疗的第一周导致生活质量较低，可能是由于焦虑，之后与SWC相比，报告的生活质量相似或更好。可以认为NPWT可能与焦虑增加有关。
本出版物的所有作者均未获得任何资金支持，也不存在与本手稿客观性相冲突的个人利益。
