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年轻成年退伍军人中的抑郁、创伤后应激障碍和酒精滥用:痛苦耐受性的跨诊断作用。

Depression, posttraumatic stress, and alcohol misuse in young adult veterans: The transdiagnostic role of distress tolerance.

作者信息

Brooks Holliday Stephanie, Pedersen Eric R, Leventhal Adam M

机构信息

RAND Corporation, 1776 Main Street, Santa Monica, CA 90407, United States.

RAND Corporation, 1776 Main Street, Santa Monica, CA 90407, United States.

出版信息

Drug Alcohol Depend. 2016 Apr 1;161:348-55. doi: 10.1016/j.drugalcdep.2016.02.030. Epub 2016 Feb 27.

Abstract

BACKGROUND

Alcohol misuse is common among young adult veterans, and is commonly associated with depression and posttraumatic stress disorder (PTSD). In fact, rates of comorbid depression, PTSD, and problem drinking are high in this population. Although distress tolerance, the capacity to experience and withstand negative psychological states, has been examined as a potential transdiagnostic factor that accounts for the development of mental health disorders, problem drinking, and the comorbidity between these presenting concerns, its role has not been evaluated in a veteran population.

METHODS

Young adult veterans were recruited for an online survey related to alcohol use. Participants (n=783) completed self-report measures of alcohol use, depression and PTSD symptoms, and distress tolerance. Mediation models were conducted to examine whether distress tolerance mediated the relationship between (1) probable PTSD, (2) probable depression, and (3) comorbid probable PTSD and depression with alcohol misuse. Moderated mediation models were conducted to examine gender as a moderator.

RESULTS

Significant bivariate associations were observed among mental health symptoms, distress tolerance, and alcohol misuse. Distress tolerance significantly mediated the relationship between probable depression and PTSD (both alone and in combination) and alcohol misuse. Evidence of moderated mediation was present for probable PTSD and probable comorbid PTSD and depression, such that the indirect effect was stronger among males.

CONCLUSIONS

These results suggest that distress tolerance may be a transdiagnostic factor explaining the comorbidity of depression and PTSD with alcohol misuse in young adult veterans. These findings may inform screening and intervention efforts with this high-risk population.

摘要

背景

酒精滥用在年轻成年退伍军人中很常见,并且通常与抑郁症和创伤后应激障碍(PTSD)相关。事实上,该人群中抑郁症、创伤后应激障碍和问题饮酒的共病率很高。尽管痛苦耐受力,即体验和承受负面心理状态的能力,已被作为一种潜在的跨诊断因素进行研究,该因素可解释心理健康障碍、问题饮酒以及这些现存问题之间的共病情况,但其在退伍军人人群中的作用尚未得到评估。

方法

招募年轻成年退伍军人参与一项与酒精使用相关的在线调查。参与者(n = 783)完成了关于酒精使用、抑郁和创伤后应激障碍症状以及痛苦耐受力的自我报告测量。进行中介模型分析,以检验痛苦耐受力是否介导了(1)可能的创伤后应激障碍、(2)可能的抑郁症以及(3)创伤后应激障碍和抑郁症共病与酒精滥用之间的关系。进行调节中介模型分析,以检验性别作为调节变量的情况。

结果

在心理健康症状、痛苦耐受力和酒精滥用之间观察到显著的双变量关联。痛苦耐受力显著介导了可能的抑郁症和创伤后应激障碍(单独和合并情况)与酒精滥用之间的关系。对于可能的创伤后应激障碍以及可能的创伤后应激障碍和抑郁症共病,存在调节中介的证据,即男性的间接效应更强。

结论

这些结果表明,痛苦耐受力可能是一个跨诊断因素,可解释年轻成年退伍军人中抑郁症和创伤后应激障碍与酒精滥用的共病情况。这些发现可能为针对这一高风险人群的筛查和干预工作提供信息。

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