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失眠严重程度作为年轻成年退伍军人心理健康症状与酒精使用之间关联的中介因素。

Insomnia severity as a mediator of the association between mental health symptoms and alcohol use in young adult veterans.

作者信息

Miller Mary Beth, DiBello Angelo M, Carey Kate B, Borsari Brian, Pedersen Eric R

机构信息

Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University School of Public Health, Box G-S121-5, Providence, RI 02912, USA.

Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University School of Public Health, Box G-S121-5, Providence, RI 02912, USA; San Francisco Veterans Affairs Health Care System, 4150 Clement Street, San Francisco, CA 94121, USA; University of California, 505 Parnassus Ave., San Francisco, CA 94143, USA.

出版信息

Drug Alcohol Depend. 2017 Aug 1;177:221-227. doi: 10.1016/j.drugalcdep.2017.03.031. Epub 2017 May 30.

Abstract

PURPOSE

Prior research has documented associations between mental health and alcohol use, mental health and insomnia, and insomnia and alcohol use. This study examined insomnia severity as a mediator of the association between mental health and alcohol-related outcomes in young adult veterans.

PROCEDURES

Veterans aged 18-34 years (N=622, 83% male) who reported drinking in the past year completed assessments at baseline and one-month follow-up as part of a larger intervention trial. Participants reported symptoms of depression and posttraumatic stress disorder (PTSD) at baseline, insomnia severity at one month, and alcohol use and related consequences at baseline and one month. Mediation analyses using bootstrapped confidence intervals were used to examine the indirect effects of baseline mental health symptoms on alcohol-related outcomes at one month via insomnia severity.

MAIN FINDINGS

Insomnia severity was associated with both drinking quantity and alcohol-related consequences. Greater depressive (but not PTSD) symptoms were associated directly with more alcohol-related consequences. Neither depressive nor PTSD symptoms had direct effects on drinking quantity when controlling for the other mental health symptoms (e.g., depressive symptoms did not predict drinking quantity when controlling for symptoms of PTSD). However, symptoms of depression and PTSD predicted drinks per week and alcohol-related consequences indirectly through insomnia severity.

CONCLUSIONS

Symptoms of depression and PTSD increase risk for alcohol use and related consequences in part by increasing symptoms of insomnia. Findings suggest that insomnia may be an appropriate target for prevention and intervention efforts among heavy-drinking Veterans reporting symptoms of depression or PTSD.

摘要

目的

先前的研究记录了心理健康与酒精使用、心理健康与失眠以及失眠与酒精使用之间的关联。本研究考察了失眠严重程度在年轻成年退伍军人心理健康与酒精相关后果之间的关联中所起的中介作用。

程序

年龄在18 - 34岁之间(N = 622,83%为男性)且报告在过去一年有饮酒行为的退伍军人作为一项更大规模干预试验的一部分,在基线和随访一个月时完成评估。参与者在基线时报告抑郁和创伤后应激障碍(PTSD)症状,在一个月时报告失眠严重程度,在基线和一个月时报告酒精使用及相关后果。使用自抽样置信区间的中介分析来检验基线心理健康症状通过失眠严重程度对一个月时酒精相关后果的间接影响。

主要发现

失眠严重程度与饮酒量及酒精相关后果均有关联。更严重的抑郁(而非PTSD)症状直接与更多酒精相关后果相关。在控制其他心理健康症状时(例如,在控制PTSD症状时,抑郁症状不能预测饮酒量),抑郁和PTSD症状对饮酒量均无直接影响。然而,抑郁和PTSD症状通过失眠严重程度间接预测每周饮酒量和酒精相关后果。

结论

抑郁和PTSD症状部分通过增加失眠症状来增加酒精使用及相关后果的风险。研究结果表明,对于报告有抑郁或PTSD症状的重度饮酒退伍军人,失眠可能是预防和干预措施的一个合适靶点。

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