Strami G, Bortul M, Cherubini M, Pella N
Ann Ital Chir. 1989;60(3):173-9; discussion 180.
The surgical treatment of the primary gastric lymphoma (P.G.L.) presents some controversial aspects still. The authors discuss the problem on the basis of the most recent data published in the literature and on their own experience concerning 14 cases of P.G.L. They confirm that surgery maintains an important role, at first, in the determination of the diagnosis exactly. The incidence of preoperative diagnosis of P.G.L. is unsatisfactory still, although increasing with the appropriate technique of endoscopic biopsies and modern immunohistochemical analysis. Moreover, the surgical approach is necessary for the definitive staging of the disease, which at the laparotomy, must be performed with these modalities: gastrectomy, regional and extra-regional lympho-adenectomy, fine needle aspiration and surgical biopsy of the liver. The extension of the gastrectomy is based on the location of the tumor. In the P.G.L. localized in the middle and in the upper stomach a total gastrectomy must be performed; on the contrary in a neoplasm localized in the lower part, a subtotal gastrectomy could be considered as a curative treatment. Integrated with chemotherapy, surgery offers appreciable results in long term survival, much better than those obtained after surgical treatment of gastric cancer.
原发性胃淋巴瘤(P.G.L.)的外科治疗仍存在一些争议性问题。作者基于文献中发表的最新数据以及他们自身关于14例P.G.L.的经验来探讨这一问题。他们证实,手术首先在准确确定诊断方面仍发挥着重要作用。尽管随着内镜活检的适当技术和现代免疫组织化学分析,P.G.L.术前诊断的发生率仍不尽人意,但有所上升。此外,手术方法对于疾病的最终分期是必要的,在剖腹手术时,必须采用以下方式进行:胃切除术、区域和区域外淋巴结清扫术、肝脏细针穿刺抽吸和手术活检。胃切除术的范围基于肿瘤的位置。对于位于胃中部和上部的P.G.L.,必须进行全胃切除术;相反,对于位于下部的肿瘤,可考虑行次全胃切除术作为根治性治疗。与化疗相结合,手术在长期生存方面能取得可观的效果,远比胃癌手术治疗后的效果要好。