Dakour Aridi Hanaa, Alami Ramzi, Tamim Hani, Shamseddine Ghassan, Fouani Tarek, Safadi Bassem
Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
Biostatistics Unit, Clinical Research Institute, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Surg Obes Relat Dis. 2016 Nov;12(9):1689-1696. doi: 10.1016/j.soard.2015.11.025. Epub 2015 Nov 27.
Long-term data of laparoscopic sleeve gastrectomy (LSG) are still scarce in the Middle East.
The aim of this study was to assess the efficacy and safety at 5 years and beyond.
Tertiary referral hospital between April 2007 and March 2015.
A retrospective review of 76 patients who underwent LSG at the senior author's institution between April 2007 and March 2010.
Mean preoperative body mass index (BMI) was 42.8±7.1 kg/m. Follow-up rates were 90.4%, 86.3%, and 77.8% at 5, 6, and 7 years, respectively. Percentage of excess weight loss (%EWL) was 69.8%±28.7% at 5 years, 70.6%±32.7% at 6 years, and 76.6%±21.2% at 7 years, respectively. Mean total weight loss was 26.5%±8.7%, 24.9%±8.8%, and 26.6%±6.0% at 5, 6, and 7 years, respectively. %EWL at 5-years was significantly higher for patients with a preoperative BMI<45 kg/m (83.1% versus 46.3%, P<.0001). LSG improved or resolved diabetes, hypertension, and asthma in 87.5%, 68%, and 81.7% of patients, respectively. New onset gastroesophageal acid reflux disease developed in 21.2% of patients. Long-term complications included hiatal hernias necessitating repair (1.4%), incisional hernias (2.7%), and symptomatic gallstones (9.6%), as well as depression necessitating admission (4.1%).
In the present patient population, LSG resulted in satisfactory %EWL and co-morbidity resolution after 5 years. The results were excellent for patients with a BMI<45 kg/m. De novo acid reflux symptoms developed in 1 of 5 patients. Cholelithiasis necessitating cholecystectomy was the most common long-term complication.
中东地区腹腔镜袖状胃切除术（LSG）的长期数据仍然稀缺。
本研究的目的是评估5年及以后的疗效和安全性。
2007年4月至2015年3月期间的三级转诊医院。
对2007年4月至2010年3月期间在资深作者所在机构接受LSG的76例患者进行回顾性研究。
术前平均体重指数（BMI）为42.8±7.1kg/m²。5年、6年和7年的随访率分别为90.4%、86.3%和77.8%。5年时超重体重减轻百分比（%EWL）分别为69.8%±28.7%，6年时为70.6%±32.7%，7年时为76.6%±21.2%。5年、6年和7年时的平均总体重减轻分别为26.5%±8.7%、24.9%±8.8%和26.6%±6.0%。术前BMI<45kg/m²的患者5年时的%EWL显著更高（83.1%对46.3%，P<0.0001）。LSG分别使87.5%、68%和81.7%的患者的糖尿病、高血压和哮喘得到改善或缓解。21.2%的患者出现新发胃食管酸反流病。长期并发症包括需要修复的食管裂孔疝（1.4%）、切口疝（2.7%）和有症状的胆结石（9.6%），以及需要住院治疗的抑郁症（4.1%）。
在本患者群体中，LSG在5年后导致了令人满意的%EWL和合并症缓解。对于BMI<45kg/m²的患者，结果非常好。五分之一的患者出现了新发酸反流症状。需要胆囊切除术的胆结石是最常见的长期并发症。
