酒渣鼻患者的角膜和结膜敏感性
Corneal and conjunctival sensitivity in rosacea patients.
作者信息
Örnek Nurgül, Karabulut Ayşe Anıl, Örnek Kemal, Onaran Zafer, Usta Gülşah
机构信息
Department of Opthalmology, Kırıkkale University, School of Medicine, Kırıkkale, Turkey.
Department of Dermatology and Venereology, Kırıkkale University, School of Medicine, Kırıkkale, Turkey.
出版信息
Saudi J Ophthalmol. 2016 Jan-Mar;30(1):29-32. doi: 10.1016/j.sjopt.2015.09.001. Epub 2015 Sep 11.
PURPOSE
To assess corneal and conjunctival sensitivity in rosacea patients.
METHODS
A total of 55 patients with rosacea and 37 control subjects participated in the study. Corneal and conjunctival sensitivity was determined by Cochet-Bonnet esthesiometer. Subjective symptoms of ocular dryness were evaluated using Ocular Surface Disease Index (OSDI). Schirmer's I test (ST), tear breakup time (tBUT) and ocular surface staining with fluorescein were carried out to measure objective signs.
RESULTS
The mean corneal and conjunctival sensitivity did not differ significantly between rosacea patients and controls (all p > 0.05). Schirmer's I test and tBUT were significantly reduced (p = 0.004 for OD and p < 0.001 for OS) and grade of ocular surface staining was significantly high (p = 0.018 for OD and p = 0.038 for OS) in rosacea patients. Corneal and conjunctival sensitivity did not show significant correlation with ST, tBUT, ocular surface staining (Oxford Schema), duration of rosacea and OSDI score.
CONCLUSIONS
Corneal and conjunctival sensitivity did not change significantly in rosacea.
目的
评估酒渣鼻患者的角膜和结膜敏感性。
方法
共有55名酒渣鼻患者和37名对照受试者参与了该研究。使用Cochet-Bonnet触觉计测定角膜和结膜敏感性。使用眼表疾病指数（OSDI）评估眼干的主观症状。进行Schirmer I试验（ST）、泪膜破裂时间（tBUT）和荧光素眼表染色以测量客观体征。
结果
酒渣鼻患者与对照者之间的平均角膜和结膜敏感性无显著差异（所有p>0.05）。酒渣鼻患者的Schirmer I试验和tBUT显著降低（右眼p = 0.004，左眼p<0.001），眼表染色分级显著升高（右眼p = 0.018，左眼p = 0.038）。角膜和结膜敏感性与ST、tBUT、眼表染色（牛津分类法）、酒渣鼻病程和OSDI评分无显著相关性。
结论
酒渣鼻患者的角膜和结膜敏感性无显著变化。
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