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尼日利亚奥孙州部分医疗机构中结核病患者的治疗依从性及挑战

Treatment compliance and challenges among tuberculosis patients across selected health facilities in Osun State Nigeria.

作者信息

Ajao K O, Ogundun O A, Afolabi O T, Ojo T O, Atiba B P, Oguntunase D O

出版信息

Afr J Med Med Sci. 2014 Dec;43 Suppl:21-9.

PMID:26949777
Abstract

BACKGROUND

Tuberculosis (TB) is a major public health problem in the world and Africa has approximately one quarter of the world's cases. One of the greatest challenges facing most TB programmes is the non-compliance to TB treatment among TB patients.

AIM

This study aimed at determining the challenges of management of tuberculosis (TB) across selected Osun State health facilities. The study employed a descriptive cross-sectional design. A semi-structured questionnaire was used to collect data from 102 TB patients in the health facilities. The instrument measured socio-demographic variables, patient related factors, socio-economic variables, health care system related factors to TB disease and treatment.

METHODS

Data were analysed and summarized using descriptive and inferential statistics. Statistical significance was placed at p < 0.05.

RESULTS

TB patients who had no formal education (χ2 = 12.941, p < 0.05), who were smoking during treatment (χ2 = 13.194, p < 0.001), who consumed alcohol during TB treatment (χ2 = 6.371, p < 0.05) and those who were HIV positive (χ2 = 23.039, p < 0.001) significantly failed to comply with TB treatment. TB patients who waited for one hour or more at heath facilities (χ2 = 21.761, p < 0.001), who reported that TB treatment should be stopped before six month (χ2 = 9.804, p < 0.05) or when patient felt better (χ2 = 35.185, p < 0.001) and travelled for 10 km or more (χ2 = 13.610, p < 0.001) significantly failed to comply with TB treatment.

CONCLUSION

This study concluded that non-compliance rate to tuberculosis treatment among TB patients in this study is high. Both health facility and patient-related factors were largely responsible.

摘要

背景

结核病是全球主要的公共卫生问题,非洲的病例数约占全球的四分之一。大多数结核病防治项目面临的最大挑战之一是结核病患者不遵守治疗方案。

目的

本研究旨在确定奥孙州部分医疗机构结核病管理面临的挑战。该研究采用描述性横断面设计。使用半结构化问卷从医疗机构的102名结核病患者中收集数据。该工具测量了社会人口统计学变量、患者相关因素、社会经济变量、与结核病疾病和治疗相关的医疗保健系统因素。

方法

使用描述性和推断性统计方法对数据进行分析和总结。统计学显著性设定为p < 0.05。

结果

未受过正规教育的结核病患者(χ² = 12.941,p < 0.05)、治疗期间吸烟的患者(χ² = 13.194,p < 0.001)、结核病治疗期间饮酒的患者(χ² = 6.371,p < 0.05)以及艾滋病毒呈阳性的患者(χ² = 23.039,p < 0.001)明显不遵守结核病治疗方案。在医疗机构等待一小时或更长时间的结核病患者(χ² = 21.761,p < 0.001)、报告结核病治疗应在六个月前停止的患者(χ² = 9.804,p < 0.05)或患者感觉好转时停止的患者(χ² = 35.185,p < 0.00

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