Hill-Taylor B, Sketris I S, Gardner D M, Thompson K
J Popul Ther Clin Pharmacol. 2016;23(1):e1-12. Epub 2016 Feb 10.
Optimization of prescribing in older adults is needed. The STOPP criteria provide a systematic way of identifying potentially inappropriate prescribing in this population. Previous research indicates poor concordance between benzodiazepine prescribing and STOPP.
To determine the extent and predictors of benzodiazepine and zopiclone (BZD-Z) pharmacy dispensations in older adults with a history of a recent fall, in concordance with STOPP.
Prescription claims data from the Nova Scotia Seniors' Phamacare Program were linked with fall-related injury data from the CIHI Discharge Abstract Database. Adults aged ≥ 66 years making a claim for a BZD-Z in the 100 days prior to fall-related hospitalization were identified. Their BZD-Z claims in the 100 days following discharge were also identified. Descriptive statistics, trend tests and logistical regression modelling were performed to examine predictors for continued use of BZD-Z post-fall.
Over 5 years, from a pool of 8,271 older adults discharged following a fall-related hospitalization, 1,789 (21.6%) had made a claim for a BZD-Z in the 100 days prior to admission. Of these, 82% were women. Younger age and female sex were predictors of continuing BZD-Z dispensations post-fall. In the 100 days following discharge, 74.2% (n=1327) made a claim for at least one BZD-Z.
BZD-Z use continued in 74% of patients following discharge from a fall-related hospitalization, representing limited concordance with the STOPP criterion. Such hospitalizations and follow-up care present an opportunity to address an ongoing modifiable risk factor.
老年患者的处方优化很有必要。STOPP标准提供了一种系统的方法来识别该人群中潜在不适当的处方。先前的研究表明苯二氮䓬类药物处方与STOPP标准之间的一致性较差。
确定近期有跌倒史的老年患者中苯二氮䓬类药物和佐匹克隆(BZD-Z)的药房配药情况与STOPP标准的符合程度及预测因素。
新斯科舍省老年人医保计划的处方报销数据与加拿大卫生信息研究所出院摘要数据库中与跌倒相关的伤害数据相关联。确定在与跌倒相关的住院前100天内申请BZD-Z的66岁及以上成年人。还确定了他们出院后100天内的BZD-Z报销情况。进行描述性统计、趋势测试和逻辑回归建模,以检查跌倒后继续使用BZD-Z的预测因素。
在5年时间里,从8271名因跌倒相关住院而出院的老年人中,有1789人(21.6%)在入院前100天内申请了BZD-Z。其中,82%为女性。年龄较小和女性是跌倒后继续使用BZD-Z配药的预测因素。出院后的100天内,74.2%(n = 1327)的人申请了至少一种BZD-Z。
在因跌倒相关住院出院后的患者中,74%继续使用BZD-Z,这表明与STOPP标准的符合程度有限。此类住院和后续护理提供了一个解决持续存在的可改变风险因素的机会。