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[伪狂犬病病毒的天然免疫逃避机制]

[Innate Immune Evasion Mechanisms of Pseudorabies Virus].

作者信息

Liu Yaozong, Rui Ping, Ma Rui, Ma Zengjun

出版信息

Bing Du Xue Bao. 2015 Nov;31(6):698-703.

Abstract

Pseudorabies is an economically important disease in a variety ot animals caused by pseudorabies virus. Since 2011, pseudorabies outbreaks occurred in many regions of China. Related researches on this virus become a hot topic in virology and veterinary. One of the difficulties for pseudorabies prevention and control is innate immune evasion. Explorations on this issue are conducive to the development of vaccine and drugs. Therefore, this review summarized the recent research progress on the mechanisms of pseudorabies virus innate immune evasion. Theoretical direction was provided on effetive prevention and control of pseudorabies owing to this review.

摘要

伪狂犬病是由伪狂犬病病毒引起的、对多种动物具有重要经济影响的疾病。自2011年以来,中国许多地区都发生了伪狂犬病疫情。关于这种病毒的相关研究成为病毒学和兽医学领域的热点话题。伪狂犬病防控的难点之一是其对先天性免疫的逃避。对这一问题的探索有助于疫苗和药物的研发。因此,本综述总结了伪狂犬病病毒先天性免疫逃避机制的最新研究进展。本综述为伪狂犬病的有效防控提供了理论指导。

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