Hu B J
Zhonghua Yi Xue Za Zhi. 1989 Oct;69(10):560-2, 38.
This paper reports the results of sampling the secretion of lower respiratory tract by protected specimen brush(PSB) via fiberoptic bronchoscope for the isolation of pathogenic organisms in laboratory and clinic. Studies in vitro showed that the technique of PSB is better than that of single shear catheter brush (SSC) or cytologic brush (CB) for anti-contamination. The specificity and sensitivity of sampling were 93% and 100% respectively. The application of PSB in the diagnosis of pneumonia in canine models revealed that both specificity and sensitivity were 100% Sampling in 18 cases of pulmonary bacterial infections and 17 cases of other pulmonary diffusing diseases indicated that the specificity and sensitivity were 86% and 94% respectively. The authors are of the opinion that PSB sampling technique has a better anti-contamination effect and can increase the isolation rate of pathogens. The PSB may be a satisfactory sampling tool in etiologic diagnosis of pulmonary infections.
本文报告了通过纤维支气管镜用防污染样本刷（PSB）采集下呼吸道分泌物，用于实验室和临床分离致病微生物的结果。体外研究表明，在防止污染方面，PSB技术优于单剪导管刷（SSC）或细胞刷（CB）。采样的特异性和敏感性分别为93%和100%。PSB在犬类肺炎模型诊断中的应用显示，特异性和敏感性均为100%。对18例肺部细菌感染和17例其他肺部弥漫性疾病进行采样表明，特异性和敏感性分别为86%和94%。作者认为，PSB采样技术具有更好的防污染效果，可提高病原体的分离率。PSB可能是肺部感染病因诊断中一种令人满意的采样工具。
