瑞士乳杆菌CAUH18的全基因组序列，这是一株源自马奶酒的潜在益生菌菌株。
Complete genome sequence of Lactobacillus helveticus CAUH18, a potential probiotic strain originated from koumiss.
作者信息
Yang Yang, An Haoran, Zhai Zhengyuan, Wang Guohong, Li Jiaxi, Hao Yanling
机构信息
The Innovation Centre of Food Nutrition and Human Health (Beijing), College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, PR China.
Key Laboratory of Functional Dairy, Co-constructed by Ministry of Education and Beijing Municipality, Beijing 100083, PR China.
出版信息
J Biotechnol. 2016 Apr 20;224:18-9. doi: 10.1016/j.jbiotec.2016.03.004. Epub 2016 Mar 4.
Here we report the complete genome sequence of Lactobacillus helveticus CAUH18, a new strain isolated from traditional fermented dairy product koumiss. Its genome has a circular 2.16Mb chromosome with no plasmid. The genome sequence indicated that this strain harbors a gene cluster involved in a novel exopolysaccharides (EPS) biosynthesis and a gene encoding cell-surface aggregation-promoting factors (APFs) to facilitate its colonization in gastrointestinal tract (GIT). This genome sequence provides a basis for further studies about its molecular genetics and probiotic functions.
在此，我们报告从传统发酵乳制品马奶酒中分离出的新菌株瑞士乳杆菌CAUH18的全基因组序列。其基因组有一个2.16Mb的环状染色体，无质粒。基因组序列表明，该菌株含有一个参与新型胞外多糖（EPS）生物合成的基因簇和一个编码细胞表面聚集促进因子（APF）的基因，以促进其在胃肠道（GIT）中的定殖。该基因组序列为进一步研究其分子遗传学和益生菌功能提供了基础。
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