Gaebel W, Buchkremer G, Häfner H, Klosterkötter J, Maier W, Möller H-J, Wölwer W
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Medizinische Fakultät, Heinrich-Heine-Universität Düsseldorf, LVR Klinikum Düsseldorf, Bergische Landstraße 2, 40629, Düsseldorf, Deutschland.
Klinik für Psychiatrie und Psychotherapie, Universität Tübingen, Tübingen, Deutschland.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Apr;59(4):412-9. doi: 10.1007/s00103-016-2311-1.
The German Research Network on Schizophrenia (GRNS) was funded by the Federal Ministry of Education and Research (BMBF) from 1999 to 2011. The aim was to obtain a better horizontal and vertical networking of German research and care facilities on schizophrenia, in order to investigate open research questions, to transfer the results into clinical practice and improve care and quality of life in patients with schizophrenia.
OBJECTIVES/METHODS: This paper describes the concept and operations of the GRNS as well as its results on the basis of selected research projects.
The GRNS comprised about 25 clinical trials of high practical relevance, which were closely interrelated regarding content, methodology and organization. The trials primarily served the development and evaluation of new and established diagnostic and therapeutic approaches, the assessment of the status quo of clinical care, as well as its improvements, together with the investigation of basic scientific questions. Many substantial results to highly relevant issues were obtained, which led or will lead to an improvement in mental health care.
Quantitative and qualitative evaluation parameters, such as scientific publications and obtaining additional grants, as well as promotion of young scientists, public relations activities, congress activities and the foundation of a European Schizophrenia Association, document the successful work of the network. Successful funding requests will allow us to continue cooperative schizophrenia research in Germany as initiated by the GRNS, without necessarily always binding these activities formally to the GRNS.
德国精神分裂症研究网络（GRNS）在1999年至2011年期间由联邦教育与研究部（BMBF）资助。其目的是在德国精神分裂症研究与护理机构之间实现更好的横向和纵向网络连接，以研究尚未解决的研究问题，将研究结果转化为临床实践，并改善精神分裂症患者的护理及生活质量。
目标/方法：本文基于选定的研究项目，描述了GRNS的概念、运作情况及其成果。
GRNS包含约25项具有高度实际相关性的临床试验，这些试验在内容、方法和组织方面紧密相关。这些试验主要用于新的和既定的诊断及治疗方法的开发与评估、临床护理现状的评估及其改进，以及基础科学问题的研究。针对高度相关问题取得了许多重要成果，这些成果已经或将会改善精神卫生保健。
诸如科学出版物、获得额外资助等定量和定性评估参数，以及对年轻科学家的培养、公关活动、大会活动和欧洲精神分裂症协会的成立，都证明了该网络的成功运作。成功的资金申请将使我们能够继续开展由GRNS发起的德国精神分裂症合作研究，而不必总是将这些活动正式与GRNS绑定。
