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一种来自木香根的新型倍半萜类化合物。

A new sesquiterpenoid from Saussurea lappa roots.

作者信息

Cao Kun, Qian Wei, Xu Yi, Zhou Zhen, Zhang Qing, Zhang Xiaofeng

机构信息

a College of Chemistry and Chemical Engineering , Chongqing University , Chongqing , P.R. China.

b Defense Key Disciplines Lab of Novel Micro-nano Devices and System Techonlogy , Chongqing University , Chongqing , P.R. China.

出版信息

Nat Prod Res. 2016 Oct;30(19):2160-3. doi: 10.1080/14786419.2016.1149708. Epub 2016 Mar 8.

Abstract

A new sesquiterpenoid, 10α-methoxyartemisinic acid (1) was isolated from Saussurea lappa roots along with two known compounds, costunolide (2) and dehydrocostus lactone (3) by high-speed countercurrent chromatography with purities of 85, 95 and 98%, respectively. Their structures were determined on the basis of spectral data including 1D and 2D NMR and HREIMS.

摘要

从木香根中分离出一种新的倍半萜类化合物10α-甲氧基青蒿酸(1),同时还通过高速逆流色谱法分离出两种已知化合物木香烯内酯(2)和去氢木香内酯(3),其纯度分别为85%、95%和98%。它们的结构是根据包括一维和二维核磁共振以及高分辨电子电离质谱在内的光谱数据确定的。

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