Garg Shivani, Mulki Ramzi, Sher Daniel
Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA.
BMJ Case Rep. 2016 Mar 8;2016:bcr2015214298. doi: 10.1136/bcr-2015-214298.
Metastatic disease from pancreatic carcinoma involving the stomach is an unusual event, and the pattern of spread in the form of linitis plastica, to our knowledge, has not been reported previously. Local recurrence after curative resection for pancreatic cancer is the most common pattern of disease. We report a case of metastatic pancreatic adenocarcinoma presenting as linitis plastica of the stomach 4 years after curative resection. A 52-year-old man presented with epigastric pain and melaena 4 years after undergoing a Whipple's procedure for a poorly-differentiated pancreatic adenocarcinoma, stage IB; T2N0M0. CT imaging of the abdomen revealed thickening of the gastric wall, and subsequent oesophagogastroduodenoscopy (OGD) revealed diffuse friable erythaematous tissue. The biopsy specimen obtained during the OGD revealed a poorly differentiated adenocarcinoma, with similar appearance to the prior specimen obtained from the pancreas.
胰腺癌转移至胃是一种罕见情况,据我们所知,以往尚未有皮革胃形式的转移模式的报道。胰腺癌根治性切除术后局部复发是最常见的疾病模式。我们报告1例在根治性切除术后4年出现胃皮革胃表现的转移性胰腺腺癌病例。一名52岁男性在因IB期(T2N0M0)低分化胰腺腺癌接受惠普尔手术4年后出现上腹部疼痛和黑便。腹部CT成像显示胃壁增厚,随后的食管胃十二指肠镜检查(OGD)发现弥漫性易碎的红斑组织。OGD期间获取的活检标本显示为低分化腺癌,外观与之前从胰腺获取的标本相似。