Liszauer A D, Wiens J J, Brownstein S, Deschênes J
Department of Ophthalmology, McGill University, Royal Victoria Hospital, Montreal.
Can J Ophthalmol. 1991 Oct;26(6):325-7.
A 59-year-old man underwent total gastrectomy for diffuse, poorly differentiated gastric adenocarcinoma diagnosed as linitis plastica. Loss of vision in the right eye 5 months later due to extensive choroidal tumours was the first indication of metastatic disease. Radiologic studies showed multiple bony metastases. The blind, painful eye was enucleated. Pathological examination of the globe showed massive metastatic mucus-secreting adenocarcinoma of the choroid, with positive immunohistochemical staining for carcinoembryonic antigen (CEA) of the foci of the more highly differentiated neoplastic cells. The plasma CEA level had been normal. The patient died 3 months after enucleation from metastatic disease.
一名59岁男性因诊断为皮革胃的弥漫性低分化胃腺癌接受了全胃切除术。5个月后，由于广泛的脉络膜肿瘤导致右眼失明，这是转移性疾病的首个迹象。放射学检查显示多处骨转移。失明且疼痛的眼睛被摘除。眼球的病理检查显示脉络膜有大量转移性黏液分泌腺癌，高分化肿瘤细胞灶的癌胚抗原（CEA）免疫组化染色呈阳性。血浆CEA水平此前一直正常。患者在眼球摘除术后3个月因转移性疾病死亡。
