León Jiménez A, Botebol Benhamou G, Muñoz Villa C, Boza García F, Rodríguez Panadero F
Med Clin (Barc). 1989 Dec 9;93(19):727-30.
Eight patients with obstructive sleep apnea syndrome were treated with continuous positive airways pressure by nasal route. The treatment was carried out in the hospital during the initial days. If the procedure was effective and the tolerance was good, the patients were discharged to continue with treatment at home. Polygraphic sleep recordings carried out 2-4 months after the beginning of therapy showed normalization of the structure and the phases of sleep, apnea and desaturation being virtually absent. After a mean follow up of 18 months the patients are asymptomatic. The treatment has been well tolerated and significant side effects have not developed.
8例阻塞性睡眠呼吸暂停综合征患者采用经鼻持续气道正压通气治疗。治疗最初几天在医院进行。如果治疗有效且耐受性良好，患者可出院回家继续治疗。治疗开始后2 - 4个月进行的多导睡眠记录显示睡眠结构和阶段正常化，几乎不存在呼吸暂停和血氧饱和度下降。平均随访18个月后，患者无症状。该治疗耐受性良好，未出现明显副作用。
