吡唑及其生物活性的当前状况。

Current status of pyrazole and its biological activities.

作者信息

Naim Mohd Javed, Alam Ozair, Nawaz Farah, Alam Md Jahangir, Alam Perwaiz

机构信息

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Shree Ganpati Institute of Technology, Ghaziabad, Uttar Pradesh, India.

出版信息

J Pharm Bioallied Sci. 2016 Jan-Mar;8(1):2-17. doi: 10.4103/0975-7406.171694.

Pyrazole are potent medicinal scaffolds and exhibit a full spectrum of biological activities. This review throws light on the detailed synthetic approaches which have been applied for the synthesis of pyrazole. This has been followed by an in depth analysis of the pyrazole with respect to their medical significance. This follow-up may help the medicinal chemists to generate new leads possessing pyrazole nucleus with high efficacy.