Gyagenda Joseph Ogavu, Ddumba Edward, Odokonyero Raymond, Kaddumukasa Mark, Sajatovic Martha, Smyth Kathyleen, Katabira Elly
Mother Kevin Post graduate Medical School, Uganda Martyr's University, Nsambya Hospital, P. O. Box 5498 Kampala, Uganda.
Department of Psychiatry, College of Health Sciences, Makerere University , P.O. Box 7072 Kampala, Uganda.
Afr Health Sci. 2015 Dec;15(4):1220-31. doi: 10.4314/ahs.v15i4.22.
The burden of stroke worldwide is increasing rapidly. There is paucity of data on post-stroke depression (PSD) among stroke survivors in Uganda, despite the high prevalence of PSD reported elsewhere.
In a cross-sectional study, we assessed adult participants with confirmed first stroke with a standardized questionnaire. The Patient Health Questionnaire-9 was used to assess for depression among non-aphasic patients while the Aphasic Depression Rating Scale was administered to aphasic patients. Univariable and multivariable analyses performed to describe associations with PSD.
Forty three females (58.9%) and 30 males (41.1%) who had a stroke participated. Fifty eight (79.5%) had ischemic strokes and 12 participants (16.4%) were aphasic. The prevalence of PSD among the study participants was 31.5%. PSD was higher among patients assessed within 6 months after the onset of stroke. PSD was strongly associated with the total Barthel index of activities of daily living (BIADL) score; p=0.001. There was no significant association between demographic characteristics and PSD.
There is a high prevalence of unrecognized post-stroke depression. Post-stroke depression was strongly associated with the patient's inability to undertake activities of daily life. There is urgent need for integration of screening for and management of post-stroke depression among stroke survivors.
全球范围内中风负担正在迅速增加。尽管其他地方报道的中风后抑郁（PSD）患病率很高，但乌干达中风幸存者中关于PSD的数据却很匮乏。
在一项横断面研究中，我们使用标准化问卷对确诊为首次中风的成年参与者进行了评估。使用患者健康问卷-9评估非失语患者的抑郁情况，同时对失语患者使用失语抑郁评定量表。进行单变量和多变量分析以描述与PSD的关联。
43名女性（58.9%）和30名男性（41.1%）中风患者参与了研究。58名（79.5%）患有缺血性中风，12名参与者（16.4%）为失语症患者。研究参与者中PSD的患病率为31.5%。中风发病后6个月内接受评估的患者中PSD患病率更高。PSD与日常生活活动的巴氏指数总分（BIADL）密切相关；p = 0.001。人口统计学特征与PSD之间无显著关联。
未被识别的中风后抑郁患病率很高。中风后抑郁与患者无法进行日常生活活动密切相关。迫切需要将中风幸存者中风后抑郁的筛查和管理整合起来。
