Gaffoor Zakir, Wand Handan, Street Renée A, Abbai Nathlee, Ramjee Gita
HIV Prevention Research Unit, South African Medical Research Council, Durban, South Africa.
The Kirby Institute, University of New South Wales, Sydney, Australia.
AIDS Res Ther. 2016 Mar 8;13:14. doi: 10.1186/s12981-016-0098-7. eCollection 2016.
Women in sub-Saharan Africa continue to be at greater risk for HIV acquisition than men. Concurrency, viz. multiple sexual partnerships that overlap over time, has been studied as a possible risk factor for HIV transmission. The aim of this study was to identify predictors of perceived male partner concurrency among sexually active, HIV negative women.
Socio-demographic and behavioural data from women enrolled in a biomedical HIV prevention clinical trial were assessed in relation to perceived male partner concurrency using the Chi squared test. Univariate and multivariate logistic regression was performed to assess the independent predictors of perceived male partner concurrency. Kaplan-Meier survival estimates were obtained for HIV and STI incidence in relation to male partner concurrency. A Cox Proportional Hazards model was used to assess the association between perceived male partner concurrency and HIV and STI incidence.
The results revealed that 29 % of women reported their male partners to be in concurrent sexual relationships, 22 % reported partners that were not engaging in concurrency, whilst 49 % reported not knowing their partners concurrency status. Older women, having never married, experiencing economic abuse, and women reporting individual concurrency, were found to be significant predictors of perceived male partner concurrency in the studied population. Perceived male partner concurrency was not found to be a significantly associated with incident HIV and STI infections in this analysis.
The study provides insight into predictors of perceived male partner concurrency among women at high risk for STI and HIV acquisition. These results may inform the design of behavioural and biomedical interventions, to address the role of multiple sexual partnerships in HIV prevention.
撒哈拉以南非洲地区的女性感染艾滋病毒的风险仍然高于男性。同时性行为，即随着时间推移重叠的多个性伴侣关系，已被作为艾滋病毒传播的一个可能风险因素进行研究。本研究的目的是确定性活跃的艾滋病毒阴性女性中，认为男性伴侣存在同时性行为的预测因素。
使用卡方检验评估参与生物医学艾滋病毒预防临床试验的女性的社会人口学和行为数据与认为男性伴侣存在同时性行为之间的关系。进行单因素和多因素逻辑回归以评估认为男性伴侣存在同时性行为的独立预测因素。获得与男性伴侣同时性行为相关的艾滋病毒和性传播感染发病率的Kaplan-Meier生存估计值。使用Cox比例风险模型评估认为男性伴侣存在同时性行为与艾滋病毒和性传播感染发病率之间的关联。
结果显示，29%的女性报告其男性伴侣存在同时性行为，22%报告伴侣不存在同时性行为，而49%报告不知道伴侣的同时性行为状况。在研究人群中，年龄较大、从未结婚、遭受经济虐待以及报告自己存在同时性行为的女性，被发现是认为男性伴侣存在同时性行为的重要预测因素。在该分析中，未发现认为男性伴侣存在同时性行为与艾滋病毒和性传播感染的新发感染有显著关联。
本研究深入了解了性传播感染和艾滋病毒感染高危女性中认为男性伴侣存在同时性行为的预测因素。这些结果可为行为和生物医学干预措施的设计提供参考，以解决多个性伴侣关系在艾滋病毒预防中的作用。
