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[原发性肺结核的治疗方法是什么?]

[Which treatment for primary tuberculosis?].

作者信息

Gallet S, Bellon G

机构信息

Clinique médicale infantile, Centre Hospitalier Lyon-Sud, France.

出版信息

Pediatrie. 1989;44(9):699-704.

PMID:2695890
Abstract

Primary tuberculosis should be treated in all cases. In adults, the total treatment course for pulmonary tuberculosis can be shortened to 6 months. If the disease is not symptomatic, the rifampicin-isoniazid combination (10 mg/kg/day each) appears to be preferable to single drug therapy. In patients with symptomatic disease, pyrazinamide (30 mg/kg/day) should be added during the first 6-8 weeks and in some cases, corticosteroid therapy is also required. The drugs are usually well tolerated, but hepatic function should be monitored.

摘要

所有原发性肺结核病例均应接受治疗。对于成年人,肺结核的总疗程可缩短至6个月。如果疾病没有症状,利福平-异烟肼联合用药(各10毫克/千克/天)似乎比单一药物治疗更可取。对于有症状的患者,在前6-8周应加用吡嗪酰胺(30毫克/千克/天),在某些情况下,还需要进行皮质类固醇治疗。这些药物通常耐受性良好,但应监测肝功能。

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