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持续血液滤过是否优于间歇性透析和血液滤过治疗?

Is continuous haemofiltration superior to intermittent dialysis and haemofiltration treatment?

作者信息

Sieberth H G, Kierdorf H

机构信息

Medizinische Klinik II, RWTH Aachen, FRG.

出版信息

Adv Exp Med Biol. 1989;260:181-92. doi: 10.1007/978-1-4684-5718-6_19.

Abstract
  1. Mortality in cases of acute renal failure has increased from roughly 30% to roughly 70% in recent decades. 2. The rise paralleled the creation of intensive care units. In such units, more seriously ill patients reach the stage of acute renal failure. Before the advent of intensive care units, these patients died before acute renal failure could occur. 3. From a theoretical viewpoint, continuous haemofiltration (CH) has substantial advantages as opposed to intermittent dialysis and haemofiltration treatment. 4. No clinical proof of the superiority of continuous haemofiltration to the intermittent techniques has yet been provided. 5. In our own patient group, total mortality for acute renal failure patients decreased following adoption of continuous haemofiltration. During a selected period of use of continuous haemofiltration for patients with an unfavourable prognosis, however, the mortality with continuous haemofiltration was higher than that with the intermittent methods.
摘要
  1. 近几十年来,急性肾衰竭病例的死亡率从大约30%上升到了大约70%。2. 这种上升与重症监护病房的设立同步。在这样的病房里,病情更严重的患者会发展到急性肾衰竭阶段。在重症监护病房出现之前,这些患者在急性肾衰竭发生之前就已经死亡。3. 从理论角度来看,与间歇性透析和血液滤过治疗相比,连续性血液滤过(CH)有诸多显著优势。4. 目前尚未有临床证据表明连续性血液滤过比间歇性技术更具优越性。5. 在我们自己的患者群体中,采用连续性血液滤过后,急性肾衰竭患者的总死亡率有所下降。然而,在为预后不良的患者选择使用连续性血液滤过的特定时期内,连续性血液滤过的死亡率高于间歇性方法。

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