Levi Linda, Werbeloff Nomi, Pugachova Inna, Yoffe Rinat, Large Matthew, Davidson Michael, Weiser Mark
Department of Psychiatry, Sheba Medical Center, Tel Hashomer, Israel.
Division of Psychiatry, University College London, England, United Kingdom.
Schizophr Res. 2016 May;173(1-2):75-8. doi: 10.1016/j.schres.2016.03.007. Epub 2016 Mar 7.
To examine variations in rates of inpatient suicide and clinical risk factors for this phenomenon.
The National Israeli Psychiatric Hospitalization Case Registry was used to study inpatient suicide. Clinical risk factors for inpatient suicide were examined in a nested case control design.
Between 1990 and 2013 there were 326 inpatient suicides, at an average of one inpatient suicide per 1614 admissions. A significant decline in rates of suicide per admission over time (p<0.001) was associated with a reduced number of beds (p<0.001) and a decline in nationwide suicide rates (p=0.001). Clinical risk factors for inpatient suicide were: affective disorders (OR=5.95), schizoaffective disorder (OR=5.27), schizophrenia (OR=3.82), previous suicide attempts (OR=2.59), involuntary hospitalization (OR=1.67), and more previous hospitalizations (OR=1.16,). A multivariate model with sensitivity of 27.3% and specificity of 95.3% for inpatient suicide, showed a positive predictive value of 0.4%.
The absolute number and rates of inpatient suicide per admission have decreased over time, probably due to the decreased number of beds lowering total time at risk. Patients with affective and psychotic disorders and with previous suicide attempts have the greatest risk of inpatient suicide. However, clinical characteristics do not enable identification of patients who are at risk for suicide.
研究住院患者自杀率的变化情况以及该现象的临床风险因素。
利用以色列国家精神病住院病例登记系统研究住院患者自杀情况。采用巢式病例对照设计对住院患者自杀的临床风险因素进行研究。
1990年至2013年间,共有326例住院患者自杀,平均每1614例入院患者中有1例自杀。随着时间推移,每次入院的自杀率显著下降(p<0.001),这与病床数量减少(p<0.001)和全国自杀率下降(p=0.001)有关。住院患者自杀的临床风险因素包括:情感障碍(比值比=5.95)、分裂情感性障碍(比值比=5.27)、精神分裂症(比值比=3.82)、既往自杀未遂(比值比=2.59)、非自愿住院(比值比=1.67)以及更多的既往住院史(比值比=1.16)。一个对住院患者自杀的敏感性为27.3%、特异性为95.3%的多变量模型显示,其阳性预测值为0.4%。
随着时间的推移,每次入院的住院患者自杀绝对数和自杀率均有所下降,这可能是由于病床数量减少降低了总风险时间。患有情感和精神障碍以及有既往自杀未遂史的患者住院自杀风险最高。然而,临床特征无法识别有自杀风险的患者。