Hoyos-Bachiloglu Rodrigo, García Álvaro, Morales Pamela S, Cerda Jaime, Talesnik Eduardo, Borzutzky Arturo
Rev Chilena Infectol. 2016 Feb;33(1):12-8. doi: 10.4067/S0716-10182016000100002.
Incidence of Kawasaki disease (KD) in Chile is rising, however the distribution of cases throughout Chile is unknown.
To describe the epidemiology of KD in Chile between years 2001 and 2011, and study the geographic distribution of KD cases throughout the country.
We reviewed national hospital discharge databases for KD cases (ICD10 code M30.3) in children < 18 years. KD admission rates per 100,000 children < 5 years were calculated for every commune, health district and region, as a proxy of KD incidence.
1,404 KD cases were registered with a national KD incidence rate of 8.7. KD incidence rate increased significantly from 5.9 in 2001-2003 to 10.4 in 2009-2011 (p < 0.001). Regions IX (Araucanía), Metropolitan and VI (O'Higgins) had the highest KD incidence (12.4, 11.1 and 10.5 respectively), and regions III (Atacama), II (Antofagasta) and XII (Magallanes), had the lowest incidence (0.8, 3.9 and 4, respectively). The Eastern Metropolitan Health District, the population with the highest socioeconomic status in Chile, had the highest KD incidence rate (19.8) and concentrated 23.9% of the country's hospital discharges for KD.
KD incidence in Chile is heterogeneous, with concentration of caseloads in the central regions and especially in the Eastern Metropolitan Health District. Geographic variations of KD in Chile could be associated with real differences in incidence or with disparities in diagnostic opportunity, and access to specialists and tertiary healthcare centers.
智利川崎病(KD)的发病率正在上升,但该国各地的病例分布情况尚不清楚。
描述2001年至2011年期间智利川崎病的流行病学情况,并研究全国川崎病病例的地理分布。
我们查阅了18岁以下儿童川崎病病例(ICD10编码M30.3)的国家医院出院数据库。计算了每个公社、卫生区和地区每10万名5岁以下儿童的川崎病入院率,作为川崎病发病率的指标。
共登记了1404例川崎病病例,全国发病率为8.7。川崎病发病率从2001 - 2003年的5.9显著上升至2009 - 2011年的10.4(p < 0.001)。第九大区(阿劳卡尼亚)、首都大区和第六大区(奥希金斯)的川崎病发病率最高(分别为12.4、11.1和10.5),第三大区(阿塔卡马)、第二大区(安托法加斯塔)和第十二大区(麦哲伦)的发病率最低(分别为0.8、3.9和4)。智利社会经济地位最高的人群所在的东首都卫生区,川崎病发病率最高(19.8),该国23.9%的川崎病住院病例集中在此。
智利川崎病发病率存在异质性,病例集中在中部地区,尤其是东首都卫生区。智利川崎病的地理差异可能与发病率的实际差异、诊断机会的差异以及获得专科医生和三级医疗中心服务的差异有关。