Trabeculectomy in eyes with unsuspected retinoblastoma.
作者信息
Chawla Bhavna, Hada Maya, Seth Rachna, Sen Seema, Gupta Viney, Kashyap Seema, Narasimhaiah Pinto C
机构信息
a Ocular Oncology & Pediatric Ophthalmology Service, Dr Rajendra Prasad Center for Ophthalmic Sciences , All India Institute of Medical Sciences , New Delhi , India.
b Pediatric Oncology Division, All India Institute of Medical Sciences , New Delhi , India.
出版信息
Ophthalmic Genet. 2016 Dec;37(4):437-440. doi: 10.3109/13816810.2015.1126610. Epub 2016 Mar 11.
BACKGROUND
To report the management and clinical outcome of children with unsuspected retinoblastoma who underwent trabeculectomy surgery.
METHODS
Three children who presented to us after trabeculectomy surgery were diagnosed with retinoblastoma. They were treated with enucleation of the affected eye. Histopathology of the enucleated eyeball showed tumor infiltration into the iris and the ciliary body in two cases, and massive choroidal invasion in the third case. Six cycles of adjuvant systemic chemotherapy with carboplatin, vincristine and etoposide were given.
RESULTS
The follow-up ranged from 18-48 months. At last follow-up, all children were alive and well, with no local recurrence or systemic metastasis.
CONCLUSIONS
The management of retinoblastoma with operated trabeculectomy is challenging due to risk of tumor dissemination. Timely intervention can result in good clinical outcome. Nevertheless, a meticulous posterior segment evaluation to rule out retinoblastoma in children presenting with buphthalmos or secondary glaucoma should always be considered.
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