Akram Durre Samin, Suleman Yasmeen, Hanif Hafsa Mohammed
Honorary Chairperson, Health, Education and Literacy Programme (HELP), Pakistan; Former Chairperson of the Department of Pediatrics, Dow University of Health Sciences, Karachi, Pakistan.
Senior Programme Manager, HELP, Karachi, Pakistan.
J Pak Med Assoc. 2016 Mar;66(3):251-5.
To evaluate the efficacy, cost-effectiveness and acceptability of a 'high-density diet made from indigenous ingredients.
The retrospective study was carried out from September 2009 to May 2010 in District Sanghar, Sindh, Pakistan. A field office was established and staff was recruited and trained. A baseline survey was done to screen for malnourished children aged 6-23 months using mid-upper arm circumference, for which a cut-off value of 115mm was adopted. The screened children with a weight-for-height z score <-3 were registered and were supplied the high-density diet and micronutrients. Their mothers were counselled on infant and young child feeding practices.
The mean age of 123 children in the study was 15.5±8.5 months, and mean weight was 5.91±1.18kg. Overall, 85(69%) children attained the target weight in a mean duration of 5.08±3.2 months. Besides, 29(23.5%) children were gaining weight, but had not achieved the target by the end of the study. The mean rate of weight-gain of children who recovered was 3.30±3.59 g/kg/day. No significant adverse effects were noted. There was no documented refusal of the therapeutic supplement. The net cost of rehabilitating a child was $34.31.
The high-density diet was reasonably efficacious in improving the nutritional status of severely malnourished children.
评估一种“由本土食材制成的高密度饮食”的疗效、成本效益和可接受性。
回顾性研究于2009年9月至2010年5月在巴基斯坦信德省桑加尔地区开展。设立了一个外地办事处，并招募和培训了工作人员。进行了一项基线调查，使用上臂中部周长筛查6至23个月的营养不良儿童，采用的临界值为115毫米。对身高别体重z评分＜-3的筛查出的儿童进行登记，并提供高密度饮食和微量营养素。对他们的母亲进行婴幼儿喂养方法方面的咨询。
研究中123名儿童的平均年龄为15.5±8.5个月，平均体重为5.91±1.18千克。总体而言，85名（69%）儿童在平均5.08±3.2个月的时间内达到了目标体重。此外，29名（23.5%）儿童体重在增加，但在研究结束时未达到目标。康复儿童的平均体重增加率为3.30±3.59克/千克/天。未观察到明显不良反应。没有记录到对治疗性补充剂的拒绝情况。使一名儿童康复的净成本为34.31美元。
高密度饮食在改善重度营养不良儿童的营养状况方面具有合理的疗效。
