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使用冷冻保存的同种异体移植物治疗由伯氏考克斯体感染的腹主动脉瘤

Treatment of an Abdominal Aortic Aneurysm Infected by Coxiella Burnetii Using a Cryopreserved Allograft.

作者信息

Jayet Jérémie, Raux Maxime, Allaire Eric, Desgranges Pascal, Cochennec Frédéric

机构信息

Department of Vascular Surgery, Henri Mondor University Hospital, Créteil, France.

Department of Vascular Surgery, Henri Mondor University Hospital, Créteil, France.

出版信息

Ann Vasc Surg. 2016 May;33:227.e9-227.e12. doi: 10.1016/j.avsg.2015.09.031. Epub 2016 Mar 9.

Abstract

Q fever is a worldwide zoonosis caused by an intracellular bacillus named Coxiella burnetii (CB) and is a rare cause of vascular infections. We report a case of abdominal aortic aneurysm infected by CB with bilateral paravertebral abscesses and contiguous spondylodiscitis treated by open repair using a cryopreserved allograft and long-term antibiotic therapy by oral doxycycline and oral hydroxychloroquine for a duration of 18 months. Twenty months after the operation, the patient had no infections signs and vascular complication.

摘要

Q热是一种由名为伯氏考克斯体(CB)的细胞内杆菌引起的全球性人畜共患病,是血管感染的罕见病因。我们报告一例由CB感染导致腹主动脉瘤并伴有双侧椎旁脓肿和连续性脊椎间盘炎的病例,该病例采用冷冻保存同种异体移植物进行开放修复治疗,并口服强力霉素和羟氯喹进行为期18个月的长期抗生素治疗。术后20个月,患者无感染迹象及血管并发症。

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