Syed Faisal F, DeSimone Christopher V, Friedman Paul A, Asirvatham Samuel J
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA; Department of Pediatrics and Adolescent Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Heart Fail Clin. 2016 Apr;12(2):273-97. doi: 10.1016/j.hfc.2015.08.022.
Percutaneous left atrial appendage (LAA) closure is being increasingly used as a treatment strategy to prevent stroke in patients with atrial fibrillation (AF) who have contraindications to anticoagulants. Several approaches and devices have been developed in the last few years, each with their own unique set of advantages and disadvantages. In this article, the published studies on surgical and percutaneous approaches to LAA closure are reviewed, focusing on stroke mechanisms in AF, LAA structure and function relevant to stroke prevention, practical differences in procedural approach, and clinical considerations surrounding management.
经皮左心耳（LAA）封堵术正越来越多地被用作一种治疗策略，以预防对抗凝剂有禁忌证的心房颤动（AF）患者发生中风。在过去几年中，已经开发了几种方法和装置，每种方法和装置都有其独特的优缺点。在本文中，我们回顾了关于LAA封堵术的外科手术和经皮方法的已发表研究，重点关注AF中的中风机制、与中风预防相关的LAA结构和功能、手术方法的实际差异以及围绕管理的临床考虑因素。
