Murai H, Yoshida M, Miura S
Breast Unit, Aichi Cancer Center Hospital, Nagoya, Japan.
Nihon Geka Gakkai Zasshi. 1989 Dec;90(12):2015-20.
The authors discuss ten cases of occult carcinoma of the breast which presented initially as the axillary node enlargement. All cases were proven as adenocarcinoma. Both mammography and ultrasonography revealed the tumor in 3 cases, while in the remaining 7 cases malignant lumps were not visualized. Multiple studies to detect an extra mammary site proved to be negative. A concealed carcinoma of the breast was found in 9 patients with careful sectioning of the resected breast specimens. Only one patient in whom carcinoma of the breast could not be detected has survived well for 6 years after the mastectomy. Parasternal node involvement was not identified in all 7 patients of who had received an extended radical mastectomy. Three patients died of the disease within 45 mo. Seven patients are free of recurrence for 1 to 10 years (average 6 1/2 Y). Prognosis of the patients in this group are as good as and/or sometimes better than those of the patients with axillary nodes pathologically positive.
作者讨论了10例最初表现为腋窝淋巴结肿大的乳腺隐匿性癌。所有病例均被证实为腺癌。乳房X线摄影和超声检查在3例中发现了肿瘤,而其余7例未发现恶性肿块。多项检测乳腺外部位的研究结果均为阴性。通过对切除的乳房标本进行仔细切片,在9例患者中发现了隐匿性乳腺癌。只有1例未检测到乳腺癌的患者在乳房切除术后存活良好达6年。在接受扩大根治性乳房切除术的所有7例患者中均未发现胸骨旁淋巴结受累。3例患者在45个月内死于该疾病。7例患者无复发1至10年(平均6.5年)。该组患者的预后与腋窝淋巴结病理阳性患者的预后一样好,甚至有时更好。