[法国首尔汉坦病毒感染相关肾综合征出血热：一例报告]
[Seoul hantavirus infection-associated hemorrhagic fever with renal syndrome in France: A case report].
作者信息
Bour A, Reynes J-M, Plaisancie X, Dufour J-F
机构信息
Service de médecine interne et post-urgence, centre hospitalier Fleyriat, 900, route de Paris, CS 90401, 01012 Bourg-en-Bresse cedex, France.
Centre national de référence des hantavirus, unité de biologie des infections virales émergentes, institut Pasteur, Centre international de recherche en infectiologie, 21, avenue Tony-Garnier, 69007 Lyon, France.
出版信息
Rev Med Interne. 2016 Jul;37(7):493-6. doi: 10.1016/j.revmed.2015.10.343. Epub 2016 Mar 9.
INTRODUCTION
Rodents are hantavirus hosts. In Europe, hantaviruses are responsible for human infections resulting in hemorrhagic fever with renal syndrome. Thousands of Puumala virus infections are reported annually in Europe, whereas human Seoul virus infections are rarely detected.
CASE REPORT
We report the case of a 38-year-old patient who presented initially with flu-like symptoms and transitory blurred vision. He developed thrombocytopenia, acute renal failure, and elevated aminotransferases levels during the disease course, but the outcome was favorable with a full recovery. Afterwards, the hantavirus serology results were indicative of Seoul virus infection.
CONCLUSION
This report serves to remind physicians to consider diagnosing hantavirus infection when observing the association of fever, acute renal failure and thrombocytopenia. Transitory blurred vision is a specific element to indicate this diagnosis.
引言
啮齿动物是汉坦病毒的宿主。在欧洲，汉坦病毒可导致人类感染，引发肾综合征出血热。欧洲每年报告数千例普马拉病毒感染病例，而人类汉城病毒感染则很少被检测到。
病例报告
我们报告一例38岁患者，最初表现为流感样症状和短暂性视力模糊。在病程中，他出现了血小板减少、急性肾衰竭和转氨酶水平升高，但预后良好，完全康复。此后，汉坦病毒血清学结果提示为汉城病毒感染。
结论
本报告旨在提醒医生，在观察到发热、急性肾衰竭和血小板减少同时出现时，要考虑诊断汉坦病毒感染。短暂性视力模糊是提示该诊断的一个特异性因素。
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