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[汉坦病毒感染作为肾综合征出血热的病因]

[Hantavirus infection as the cause of haemorrhagic fever with renal syndrome].

作者信息

Redal-Baigorri Belén, Chen Nielsen Xiaohui, Martin-Iguacel Raquel

机构信息

Nefrologisk Afdeling, Roskilde Sygehus, Køgevej 7-13, Roskilde.

出版信息

Ugeskr Laeger. 2012 Oct 29;174(44):2710-4.

Abstract

Hantavirus is an RNA virus that can cause potentially fatal pulmonary and renal diseases in humans. Infections with Hantaviruses occur through inhalation of aerosol from rodent faeces, urine or saliva. The predominant virus type in Denmark is the Puumala virus, which causes the mildest form of haemorrhagic fever with renal syndrome, the so-called nephropathia epidemica (NE) with good prognosis (mortality 0.1-0.4%). The incidence of Hantavirus-infection in Denmark is about ten cases a year. The diagnosis of Hantavirus-infection is based on serology and/or polymerase chain reaction in blood or urine.

摘要

汉坦病毒是一种RNA病毒,可导致人类潜在致命的肺部和肾脏疾病。感染汉坦病毒是通过吸入来自啮齿动物粪便、尿液或唾液的气溶胶。丹麦主要的病毒类型是普马拉病毒,它引起肾综合征出血热最轻微的形式,即所谓的流行性肾病(NE),预后良好(死亡率0.1-0.4%)。丹麦汉坦病毒感染的发病率约为每年10例。汉坦病毒感染的诊断基于血液或尿液中的血清学和/或聚合酶链反应。

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