Morris R, Rethnam U, Russ B, Topliss C
Swansea University Medical School, Swansea University, Swansea, UK.
Department of Trauma and Orthopaedic Surgery, Morriston hospital, Swansea, UK.
Eur J Trauma Emerg Surg. 2017 Jun;43(3):337-342. doi: 10.1007/s00068-016-0655-8. Epub 2016 Mar 14.
Hip fractures in the elderly represent a major source of morbidity and mortality, with allogeneic blood transfusions (ABTs) associated with increased mortality. This study assesses the ABT requirements between the most common patterns of hip fracture; intertrochanteric (IT) and intracapsular (IC). The impact of operation type on transfusion rates was also assessed.
A retrospective study was performed for all patients entered on the national hip fracture database over 1 year in a teaching hospital. Records of 559 patients were reviewed and, following exclusion criteria, 474 were evaluated (198 IT, 276 IC). Baseline haematological parameters and ABTs were identified using hospital systems. Analysis was performed in SPSS, using independent samples t tests, one-way ANOVAs and Chi square tests.
Patient groups were matched on gender, anaesthetic type, American Society of Anesthesiologist (ASA) grade, cognitive score and coagulation parameters. A significantly greater proportion of IT patients required an ABT during admission (39.4 vs. 22.5 %, p < 0.001). For IT fractures a greater proportion of patients required an ABT when undergoing an intramedullary nail operation compared with those requiring a dynamic hip screw (67.4 vs. 32.0 %, p < 0.001). Similarly, for IC fractures transfusion rates in patients undergoing an internal fixation were significantly lower than those undergoing hemiarthroplasty or arthroplasty (9.4 vs. 26.4 vs. 20.8 %, p = 0.033).
Patients with IT hip fractures are significantly more likely to require an ABT than those with IC hip fractures. Patients undergoing an intramedullary nail for IT fractures have significantly higher transfusion rates than for other types of operation.
老年髋部骨折是发病和死亡的主要原因,异体输血(ABT)与死亡率增加相关。本研究评估了最常见的髋部骨折类型(转子间骨折(IT)和囊内骨折(IC))之间的ABT需求量。还评估了手术类型对输血率的影响。
对一家教学医院1年内纳入国家髋部骨折数据库的所有患者进行回顾性研究。回顾了559例患者的记录,根据排除标准,对474例患者进行了评估(198例IT骨折,276例IC骨折)。使用医院系统确定基线血液学参数和ABT情况。在SPSS中进行分析,采用独立样本t检验、单因素方差分析和卡方检验。
患者组在性别、麻醉类型、美国麻醉医师协会(ASA)分级、认知评分和凝血参数方面相匹配。IT骨折患者在入院期间需要ABT的比例显著更高(39.4%对22.5%,p<0.001)。对于IT骨折,与需要动力髋螺钉的患者相比,接受髓内钉手术的患者需要ABT的比例更高(67.4%对32.0%,p<0.001)。同样,对于IC骨折,接受内固定的患者输血率显著低于接受半髋关节置换术或关节置换术的患者(9.4%对26.4%对20.8%,p=0.033)。
IT髋部骨折患者比IC髋部骨折患者更有可能需要ABT。接受IT骨折髓内钉手术的患者输血率显著高于其他类型手术的患者。