Partola Kostyantyn R, Lykotrafitis George
University of Connecticut, Storrs, United States.
University of Connecticut, Storrs, United States.
J Biomech. 2016 May 3;49(7):1221-1224. doi: 10.1016/j.jbiomech.2016.02.035. Epub 2016 Mar 2.
Data processing of force-displacement curves generated by atomic force microscopes (AFMs) for elastic moduli and unbinding event measurements is very time consuming and susceptible to user error or bias. There is an evident need for consistent, dependable, and easy-to-use AFM data processing software. We have developed an open-source software application, the force review automation environment (or FRAME), that provides users with an intuitive graphical user interface, automating data processing, and tools for expediting manual processing. We did not observe a significant difference between manually processed and automatically processed results from the same data sets.
用于弹性模量和脱粘事件测量的原子力显微镜（AFM）生成的力-位移曲线的数据处理非常耗时，并且容易受到用户错误或偏差的影响。显然需要一致、可靠且易于使用的AFM数据处理软件。我们开发了一个开源软件应用程序，即力审查自动化环境（或FRAME），它为用户提供直观的图形用户界面、自动化数据处理以及加快手动处理的工具。我们没有观察到来自相同数据集的手动处理结果和自动处理结果之间存在显著差异。
