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使用亚甲蓝作为标记物寻找和清除儿童软组织中嵌入的微小金属异物:一项随机对照试验。

Using methylene blue as a marker to find and remove tiny metallic foreign bodies embedded in the soft tissues of children: A randomised controlled trial.

机构信息

Department II of Orthopaedics, China International Science and Technology Cooperation base of Child development and Critical Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Children's Hospital of Chongqing Medical University, Chongqing 40014, China.

出版信息

Int J Surg. 2016 May;29:43-8. doi: 10.1016/j.ijsu.2016.03.018. Epub 2016 Mar 11.

Abstract

BACKGROUND

Embedment of metallic foreign bodies in the soft tissues is commonly encountered in the emergency room. Most foreign bodies are easily removed, but removal is difficult if the foreign body is very small or deeply embedded.

OBJECTIVE

To determine the usefulness of methylene blue staining in the surgical removal of tiny metallic foreign bodies embedded in the soft tissue.

METHODS

This prospective study involved 41 children treated between May 2007 and May 2012. The patients were randomly divided into a methylene blue group and a control group. In the control group, foreign bodies were located using a C-arm and removed via direct incision. In the methylene blue group, foreign bodies were located using a C-arm, marked with an injection of methylene blue and then removed surgically. The clinical outcomes, complications, operation time, surgical success rate, incision length, frequency of C-arm use, and length and depth of the foreign body were compared between the two groups.

RESULTS

The surgical success rate was significantly higher in the methylene blue group. The average operation time was significantly shorter in the methylene blue group. The C-arm was used significantly less frequently in the methylene blue group than in the control group. The incision length was significantly shorter in the methylene blue group than in the control group.

CONCLUSIONS

Methylene blue staining facilitated the location and removal of tiny metallic foreign bodies from the soft tissue, and significantly reduced operation time, incision length and radiation exposure compared to the conventional method.

摘要

背景

金属异物嵌入软组织在急诊室中很常见。大多数异物很容易取出,但如果异物非常小或深深嵌入,则取出会很困难。

目的

确定亚甲蓝染色在手术切除软组织中细小金属异物中的应用价值。

方法

这是一项前瞻性研究,共纳入 2007 年 5 月至 2012 年 5 月期间治疗的 41 名儿童患者。将患者随机分为亚甲蓝组和对照组。在对照组中,使用 C 臂定位异物并通过直接切开取出。在亚甲蓝组中,使用 C 臂定位异物,注射亚甲蓝标记,然后手术取出。比较两组的临床结果、并发症、手术时间、手术成功率、切口长度、C 臂使用频率以及异物的长度和深度。

结果

亚甲蓝组的手术成功率显著更高。亚甲蓝组的平均手术时间明显更短。亚甲蓝组的 C 臂使用频率明显低于对照组。亚甲蓝组的切口长度明显短于对照组。

结论

亚甲蓝染色有助于定位和取出软组织中的细小金属异物,与传统方法相比,可显著缩短手术时间、切口长度和减少辐射暴露。

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