Walters M D
Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio.
Obstet Gynecol Clin North Am. 1989 Dec;16(4):773-85.
The two functions of the lower urinary tract are storage of urine within the bladder and timely expulsion of urine from the urethra. Bladder filling occurs with little or no increase in intravesical pressure, despite large increases in urine volume. This process, called accommodation, results from viscoelastic properties of the bladder wall and reflex inhibition of detrusor contractility. Urinary continence is maintained at rest by outflow resistance generated by the urethral sphincteric mechanism. With increases in intra-abdominal pressure, urethral resistance is augmented by passive pressure transmission to the bladder neck and proximal urethra and possibly by reflex muscular activity within the urogenital diaphragm. Normal voiding is a reflex act under voluntary control that involves relaxation of the urethra and sustained contraction of the bladder until emptying is complete. The ICS has classified lower urinary tract dysfunction as disorders of the filling or storage phase and as disorders of the emptying phase. Although urodynamic testing is not always necessary, some evaluation of both bladder and urethral function in each phase is required for accurate diagnosis.
下尿路有两项功能,即尿液在膀胱内储存以及尿液从尿道及时排出。尽管尿量大幅增加,但膀胱充盈时膀胱内压仅有轻微升高或无升高。这个过程称为顺应性,它源于膀胱壁的粘弹性特性以及逼尿肌收缩力的反射性抑制。在静息状态下,尿道括约肌机制产生的流出阻力维持尿失禁。随着腹内压升高,尿道阻力通过被动压力传递至膀胱颈和近端尿道以及可能通过泌尿生殖膈内的反射性肌肉活动而增强。正常排尿是一种在自主控制下的反射行为,包括尿道松弛和膀胱持续收缩直至排空完成。国际尿控学会(ICS)将下尿路功能障碍分类为充盈或储存期障碍以及排空期障碍。尽管并非总是需要进行尿动力学检查,但为了准确诊断,需要对每个阶段的膀胱和尿道功能进行一些评估。