Pankova V B, Fedina I N, Serebryakov P V, Preobrazhenskaya E A, Grishin O N
All-Russian Research Institute of Railway Hygiene, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russsia, 125497.
Institute of General and Occupational Pathology, F.F. Erisman Federal Research Centre of Hygiene, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Mytishchi, Moscow region, Russia, 141014.
Vestn Otorinolaringol. 2015;80(6):28-31. doi: 10.17116/otorino201580628-31.
The objective of the present work was to develop the scientifically sound criteria for the evaluation of the occupational risks bearing in mind the high frequency of pathological changes in the ciliary epithelium of the upper respiratory tract in the employees engaged in the dust-producing industries. It was proposed to consider an increase of the SIgA level, alkaline shift in nasal secretion pH, elevation of body temperature, slowdown of the mucociliary transport, disintegration of the epithelial mucous membrane, and high frequency of its inflammatory and dystrophic changes as the criteria for early diagnostics of developing pathology of the upper respiratory tract. We have developed the method for the score-based evaluation of the risk of formation of pathological changes in the upper respiratory tract of the employees engaged in the dust-producing industries. This method can be used to enhance the effectiveness of the preventive and health-promoting measures.
本研究的目的是制定科学合理的职业风险评估标准，同时考虑到从事粉尘作业行业的员工上呼吸道纤毛上皮病理变化的高发性。建议将分泌型免疫球蛋白A（SIgA）水平升高、鼻分泌物pH值碱化、体温升高、黏液纤毛运输减慢、上皮黏膜崩解以及其炎症和营养不良性变化的高发性作为上呼吸道疾病早期诊断的标准。我们已经开发出一种基于评分的方法，用于评估从事粉尘作业行业的员工上呼吸道病理变化形成的风险。该方法可用于提高预防和促进健康措施的有效性。
