Vizioli R
Recenti Prog Med. 1989 Dec;80(12):653-8.
Any attempt to classify and to understand the basic mechanism underlying the neurological symptoms as pyramidal and/or sensitive, should start from the fundamental laws of nervous system functioning: 1) the law of reciprocal innervation of Sherrington; 2) the law of hierarchy of levels of Jackson and 3) the law of supersensitivity of deafferented structures of Cannon. Paresis on one side, Jacksonian jerks on the other side represent two opposite conditions known respectively as negative and positive symptoms of corticomotor involvement. Unluckly involuntary movements cannot be explained with these three laws. They are the clinical expression of the disorganization and disintegration of functions: a true disregulation unrespectful of laws and general principles. They must be considered as the result of conflicts of antagonist functions controlling each other, i.e. tremor, chorea, myoclonus, torsion spasm etc. The author emphasizes the clinical-descriptive aspect of the problem.
任何试图对神经系统症状进行分类并理解其作为锥体束和/或感觉症状基础的基本机制的尝试,都应从神经系统功能的基本规律入手:1)谢灵顿的交互神经支配定律;2)杰克逊的层次水平定律;3)坎农的去传入结构超敏定律。一侧的轻瘫,另一侧的杰克逊癫痫发作代表两种相反的情况,分别称为皮质运动受累的阴性和阳性症状。不幸的是,这三条定律无法解释不自主运动。它们是功能紊乱和瓦解的临床表现:一种真正无视规律和一般原则的失调。它们必须被视为相互控制的拮抗功能冲突的结果,即震颤、舞蹈症、肌阵挛、扭转痉挛等。作者强调了该问题的临床描述方面。