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无缝合主动脉瓣:单中心的早期和中期结果

Sutureless Aortic Valve: Early and Mid-Term Results at a Single Center.

作者信息

Shalabi Amjad, Raanani Ehud, Shinfeld Amihai, Kuperstein Rafael, Kogan Alexander, Lipey Alexander, Nachum Eyal, Spiegelstein Dan

出版信息

Isr Med Assoc J. 2016 Feb;18(2):119-23.

Abstract

UNLABELLED

Background: Prolonged life expectancy has increased the number of elderly high risk patients referred for surgical aortic valve replacement (AVR). These referred high risk patients may benefit from sutureless bioprosthesis procedures which reduce mortality and morbidity.

OBJECTIVES

To present our initial experience with sutureless aortic bioprotheses, including clinical and echocardiographic results, in elderly high risk patients referred for AVR.

METHODS

Forty patients (15 males, mean age 78 ± 7 years) with symptomatic severe aortic stenosis underwent AVR with the 3F Enable or Perceval sutureless bioprosthesis during the period December 2012 to May 2014. Mean logistic EuroScore was 10 ± 3%. Echocardiography was performed preoperatively, intraoperatively, at discharge and at follow-up.

RESULTS

There was no in-hospital mortality. Nine patients (22%) underwent minimally invasive AVR via a right anterior mini-thoracotomy and one patient via a J-incision. Four patients underwent concomitant coronary aortic bypass graft, two needed intraoperative repositioning of the valve, one underwent valve exchange due to inappropriate sizing, three (7.5%) had a perioperative stroke with complete resolution of neurologic symptoms, and one patient (2.5%) required permanent pacemaker implantation due to complete atrioventricular block. Mean preoperative and postoperative gradients were 44 ± 14 and 13 ± 5 mmHg, respectively. At follow-up, 82% of patients were in New York Heart Association functional class I and II.

CONCLUSIONS

Sutureless AVR can be used safely in elderly high risk patients with relatively low morbidity and mortality. The device can be safely implanted via a minimally invasive incision. Mid-term hemodynamic results are satisfactory, demonstrating significant clinical improvement.

摘要

未标注

背景:预期寿命的延长使得接受外科主动脉瓣置换术(AVR)的老年高危患者数量增加。这些被转诊的高危患者可能受益于减少死亡率和发病率的无缝合生物假体手术。

目的

介绍我们在转诊接受AVR的老年高危患者中使用无缝合主动脉生物假体的初步经验,包括临床和超声心动图结果。

方法

2012年12月至2014年5月期间,40例(15例男性,平均年龄78±7岁)有症状的严重主动脉瓣狭窄患者接受了使用3F Enable或Perceval无缝合生物假体的AVR手术。平均逻辑欧洲心脏手术风险评估系统(EuroScore)为10±3%。术前、术中、出院时及随访时均进行超声心动图检查。

结果

无院内死亡。9例(22%)患者通过右前微创胸廓切开术接受微创AVR,1例通过J形切口接受手术。4例患者同时进行了冠状动脉搭桥术,2例需要术中重新定位瓣膜,1例因尺寸不合适进行了瓣膜置换,3例(7.5%)发生围手术期卒中,神经症状完全缓解,1例(2.5%)因完全性房室传导阻滞需要植入永久性起搏器。术前和术后平均压差分别为44±14 mmHg和13±5 mmHg。随访时,82%的患者纽约心脏协会心功能分级为I级和II级。

结论

无缝合AVR可安全用于老年高危患者,发病率和死亡率相对较低。该装置可通过微创切口安全植入。中期血流动力学结果令人满意,显示出显著的临床改善。

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