1例在单一抗血小板治疗下，药物涂层球囊冠状动脉血管成形术治疗支架内再狭窄后发生亚急性支架血栓形成的病例。

A case of subacute stent thrombosis after drug-coated balloon coronary angioplasty for in-stent restenosis under single anti-platelet therapy.

作者信息

Kagawa Yuzo, Shiode Nobuo, Kawase Tomoharu, Tamekiyo Hiromichi, Okimoto Tomokazu, Hayashi Yasuhiko

机构信息

Division of Cardiology, Cardiovascular Center, Akane Foundation Tsuchiya General Hospital, 3-30 Nakashima-cho, Nakaku, Hiroshima, 730-8655, Japan.

出版信息

Cardiovasc Interv Ther. 2017 Apr;32(2):170-173. doi: 10.1007/s12928-016-0386-0. Epub 2016 Mar 15.

DOI:10.1007/s12928-016-0386-0

PMID:26979600

Abstract

This report describes a case of subacute stent thrombosis (SAT) after drug-coated balloon (DCB). A 79-year-old male was investigated for stable angina. An in-stent restenosis (ISR) lesion was detected by coronary angiography. A skin reaction related to the anti-platelet agent thienopyridine was also observed at this time. Therefore, DCB was used to treat the ISR lesion under single anti-platelet therapy (aspirin). However, 3 days after percutaneous coronary intervention, SAT occurred. OCT did not reveal the underlying cause of SAT. Further data are needed to clarify the optimal duration of dual anti-platelet therapy after DCB.

摘要

本报告描述了1例药物涂层球囊（DCB）术后亚急性支架血栓形成（SAT）的病例。一名79岁男性因稳定性心绞痛接受检查。冠状动脉造影检测到支架内再狭窄（ISR）病变。此时还观察到与抗血小板药物噻吩吡啶相关的皮肤反应。因此，在单一抗血小板治疗（阿司匹林）下，使用DCB治疗ISR病变。然而，经皮冠状动脉介入治疗后3天发生了SAT。光学相干断层扫描（OCT）未揭示SAT的潜在原因。需要进一步的数据来阐明DCB术后双联抗血小板治疗的最佳持续时间。