我们准备好进行注射了吗？卵胞浆内单精子注射中的个体化累积和控制图训练。
Are we ready to inject? Individualized LC-CUSUM training in ICSI.
作者信息
Durban Mercè, García Désireé, Obradors Albert, Vernaeve Valerie, Vassena Rita
机构信息
Clinica EUGIN, Travessera de les Corts 322, 08029, Barcelona, Spain.
Fundació EUGIN, Travessera de les Corts 314, 08029, Barcelona, Spain.
出版信息
J Assist Reprod Genet. 2016 Aug;33(8):1009-15. doi: 10.1007/s10815-016-0686-4. Epub 2016 Mar 16.
PURPOSE
The objective of this prospective, single center study was to develop a personalized training scheme for intracytoplasmic sperm injection (ICSI) through the use of learning curve-cumulative summation (LC-CUSUM), which allows to tailor training to the trainee performance, and to validate it against the performance of experienced embryologists.
METHODS
Five trainees microinjected latex microspheres (LM) into vitro matured oocytes. A microinjection was considered successful when the oocyte did not lyse in the 24 h following the injection.
RESULTS
Each trainee became proficient at ICSI after a variable number of injections, ranging from 35 to 80. Trainees that achieved proficiency went on to perform ICSI with human gametes in a clinical setting with proficiency comparable to that of experienced embryologists.
CONCLUSIONS
We show that LC-CUSUM based personalized ICSI training is feasible and allows trainees to be as proficient as trained embryologists when treating actual patients.
目的
这项前瞻性单中心研究的目的是通过使用学习曲线累积求和法（LC-CUSUM）来制定个性化的卵胞浆内单精子注射（ICSI）培训方案，该方法能够根据受训者的表现调整培训，并与经验丰富的胚胎学家的表现进行验证。
方法
五名受训者将乳胶微球（LM）显微注射到体外成熟的卵母细胞中。当卵母细胞在注射后24小时内未裂解时，显微注射被认为是成功的。
结果
每位受训者在进行了35至80次不等的注射后都熟练掌握了ICSI技术。达到熟练程度的受训者随后在临床环境中对人类配子进行ICSI操作，其熟练程度与经验丰富的胚胎学家相当。
结论
我们表明，基于LC-CUSUM的个性化ICSI培训是可行的，并且在治疗实际患者时，受训者能够与训练有素的胚胎学家一样熟练。
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