Arpin David J, Davies Brenda L, Kurz Max J
Department of Physical Therapy, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, NE, United States.
Department of Physical Therapy, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, NE, United States.
Gait Posture. 2016 Mar;45:170-4. doi: 10.1016/j.gaitpost.2016.02.001. Epub 2016 Feb 6.
To quantify the precision of the steady-state isometric control of the ankle plantarflexors musculature of individuals with multiple sclerosis (MS), and to evaluate if the precision is related to the mobility impairments.
Individuals with MS and healthy adults performed a submaximal steady-state isometric contraction with the ankle plantarflexors. The coefficient of variation was used to assess the amount of variability or error in the precision of the torques generated by the ankle plantarflexor musculature. The participants also walked across a digital mat at their preferred and fast-as-possible walking speeds, which recorded their spatiotemporal gait kinematics.
The individuals with MS: (1) had reduced maximal voluntary torques at the ankle, (2) a greater amount of variability in the precision of the isometric ankle torques, (3) altered and more variable spatiotemporal gait kinematics, and (4) a greater amount of variability in the isometric ankle torques were related to a slower walking speed and cadence, shorter step length and a greater amount of gait variability.
These results further fuels the impression that a reduction in control of the ankle joint musculature may be a key factor in the mobility and balance impairments seen in individuals with MS.
量化多发性硬化症（MS）患者踝关节跖屈肌稳态等长控制的精度，并评估该精度是否与运动功能障碍有关。
MS患者和健康成年人对踝关节跖屈肌进行次最大稳态等长收缩。变异系数用于评估踝关节跖屈肌产生的扭矩精度中的变异性或误差量。参与者还以他们偏好的和尽可能快的步行速度走过一个数字垫，该数字垫记录了他们的时空步态运动学数据。
MS患者：（1）踝关节最大自主扭矩降低，（2）等长踝关节扭矩精度的变异性更大，（3）时空步态运动学改变且变异性更大，（4）等长踝关节扭矩的更大变异性与较慢的步行速度和步频、较短的步长以及更大的步态变异性有关。
这些结果进一步加深了这样一种印象，即踝关节肌肉组织控制能力的下降可能是MS患者运动和平衡障碍的一个关键因素。
