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[关于人类神经自体移植成功的结论]

[Conclusions apropos the successes of the autotransplantation of human nerves].

作者信息

Grigorovich K A

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1989 Nov-Dec(6):19-23.

PMID:2698036
Abstract

Good results of autotransplantation of nerves in 5 patients under unfavourable conditions are reported. The author puts the question as to how is it that in a much lesser number of newly-formed fibres in the peripheral segment after autotransplantation with loss of fibres at two levels, the clinical results may sometimes be excellent in relation to restoration of movements and trophicity. A conclusion is drawn on the need for further morphological examinations of the intratruncal structure and regeneration of nerves as well as biochemical studies revealing the mechanism of the action of the factor of nerve growth. The application of an epineural suture under control of a magnifying lens with the use of the suitable microsurgical instruments and suture material is still the method of choice in most cases with nerve injuries.

摘要

报告了5例在不利条件下进行神经自体移植的良好结果。作者提出了这样一个问题:在两级纤维缺失的自体移植后,外周段新形成的纤维数量要少得多,然而在运动和营养恢复方面,临床结果有时却可能非常出色,这是怎么回事呢?得出的结论是,需要对神经的躯干内结构和再生进行进一步的形态学检查,以及进行生化研究以揭示神经生长因子的作用机制。在放大透镜的控制下,使用合适的显微外科器械和缝合材料进行神经外膜缝合,在大多数神经损伤病例中仍然是首选方法。

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1
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Zh Vopr Neirokhir Im N N Burdenko. 1989 Nov-Dec(6):19-23.
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