Joshipura Vaibhavi, Mahantesha S, Subbaiah Shobha Krishna, Lakkasetty Yogesh T
Department of Periodontics, Sri Rajiv Gandhi Dental College and Hospital, Bengaluru, Karnataka, India.
Department of Periodontics, Faculty of Dental Science, M. S. Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
J Oral Maxillofac Pathol. 2015 Sep-Dec;19(3):408. doi: 10.4103/0973-029X.174633.
Orofacial granulomatosis (OFG) comprises a group of diseases characterized by noncaseating granulomatous inflammation affecting the soft tissues of the oral and maxillofacial region. It is important to establish the diagnosis accurately because this condition is sometimes a manifestation of many systemic conditions like Crohn's disease or sarcoidosis. The clinical outcome of OFG patients continues to be unpredictable. Current therapies remain unsatisfactory. This article reports a rare case of isolated OFG with langhans type giant cells and inflammatory infiltrate without any systemic involvement, in which the condition was a manifestation of pregnancy. The diagnostic approach to and the treatment of OFG are reviewed.
口面部肉芽肿病（OFG）是一组以非干酪样肉芽肿性炎症累及口腔颌面部软组织为特征的疾病。准确做出诊断很重要，因为这种情况有时是许多全身性疾病如克罗恩病或结节病的一种表现。OFG患者的临床结局仍然不可预测。目前的治疗方法仍不尽人意。本文报告了一例罕见的孤立性OFG病例，伴有朗汉斯型巨细胞和炎症浸润，无任何全身受累情况，该病例是妊娠的一种表现。本文对OFG的诊断方法和治疗进行了综述。
