Voukalis Christos, Lip Gregory Y H, Shantsila Eduard
University of Birmingham, Institute of Cardiovascular Sciences, City Hospital, Birmingham B18 7QH, UK.
EBioMedicine. 2016 Jan 15;4:26-39. doi: 10.1016/j.ebiom.2016.01.017. eCollection 2016 Feb.
Ischaemic strokes resulting from atrial fibrillation (AF) constitute a devastating condition for patients and their carers with huge burden on health care systems. Prophylactic treatment against systemic embolization and ischaemic strokes is the cornerstone for the management of AF. Effective stroke prevention requires the use of the vitamin K antagonists or non-vitamin K oral anticoagulants (NOACs). This article summarises the latest developments in the field of stroke prevention in AF and aims to assist physicians with the choice of oral anticoagulant for patients with non-valvular AF with different risk factor profile.
心房颤动（AF）引发的缺血性中风对患者及其护理人员而言是一种极具破坏性的疾病，给医疗保健系统带来了巨大负担。针对全身栓塞和缺血性中风的预防性治疗是房颤管理的基石。有效的中风预防需要使用维生素K拮抗剂或非维生素K口服抗凝剂（NOACs）。本文总结了房颤中风预防领域的最新进展，旨在帮助医生为具有不同风险因素的非瓣膜性房颤患者选择口服抗凝剂。
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