Yamasaki Kei, Yatera Kazuhiro, Kato Kaori, Noguchi Shingo, Kawanami Toshinori, Fukuda Kazumasa, Naito Keisuke, Akata Kentaro, Ishimoto Hiroshi, Taniguchi Hatsumi, Mukae Hiroshi
Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan.
Intern Med. 2016;55(6):703-7. doi: 10.2169/internalmedicine.55.5124. Epub 2016 Mar 15.
A 23-year-old Japanese woman was admitted to A hospital due to pneumonia. IgM for Mycoplasma pneumoniae was positive, and the patient was treated with imipenem/cilastatin, clindamycin, pazufloxacin and minocycline. However, both the chest radiological findings and the symptoms became exacerbated, and she was therefore transferred to our hospital. The bronchoalveolar lavage fluid was obtained, and a 16S rRNA gene sequencing analysis revealed a monobacterial infection of Mycoplasma pneumoniae. Therefore, corticosteroid treatment in addition to minocycline was administered, and the patients symptoms, laboratory data and chest radiographs improved. Corticosteroid therapy may therefore be considered for patients with refractory M. pneumoniae pneumonia.
一名23岁的日本女性因肺炎入住A医院。肺炎支原体IgM呈阳性，患者接受了亚胺培南/西司他丁、克林霉素、帕珠沙星和米诺环素治疗。然而，胸部放射学检查结果和症状均加重，因此她被转至我院。获取了支气管肺泡灌洗液，16S rRNA基因测序分析显示为肺炎支原体单菌感染。因此，除米诺环素外还给予了皮质类固醇治疗，患者的症状、实验室数据和胸部X光片均有所改善。因此，对于难治性肺炎支原体肺炎患者可考虑使用皮质类固醇疗法。
