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超声引导下输卵管再通术与门诊宫腔镜下输卵管开口扩张术治疗近端输卵管阻塞患者妊娠结局的比较

Comparison of Pregnancy Outcome between Ultrasound- Guided Tubal Recanalization and Office-Based Microhysteroscopic Ostial Dilatation in Patients with Proximal Blocked Tubes.

作者信息

Seyam Emaduldin Mostafa, Hassan Momen Mohamed, Tawfeek Mohamed Sayed Gad Mohamed, Mahmoud Hazem Salah, Ibrahim Mostafa Gamal

机构信息

Department of Obstetrics and Gynecology, College of Medicine, El Minya University, Minya, Egypt.

Department of Obstetrics and Gynecology, Al Fayoum General Hospital, Faiyum, Egypt.

出版信息

Int J Fertil Steril. 2016 Jan-Mar;9(4):497-505. doi: 10.22074/ijfs.2015.4608. Epub 2015 Dec 23.

Abstract

BACKGROUND

The current research to the best of my knowledge is the first to compare the pregnancy outcome between ultrasound-guided tubal recanalization (UGTR) using a special fallopian tubal catheter, and office-based micrhysteroscopic ostial dilatation (MHOD) using the same tubal catherter in infertile women with previously diagnosed bilateral proximal tubal obstruction (PTO).

MATERIALS AND METHODS

This prospective study reported the pregnancy outcomes for 200 women in private infertility care center in Arafa hospital in Fayoum and in El Minya University Hospital in the period between January 2010 and October 2013 treated as outpatients for their bilateral PTO after the routine hysterosalpingography (HSG). A Cook's catheter, special fallopian tubal catheter, were used to recanalize the blocked tubes in 100 women (group A) under UGTR, and the same Cook's tubal catheter was used through 2mm microhysteroscope to cannulate both ostia using MHOD in another 100 women (group B). Pregnancy outcome was determined after the procedures for a 12-month period follow-up.

RESULTS

The number of the recanalization of PTO was not significantly different between two groups. As of the 200 blocked fallopian tubes in group A, 140 tubes (70%) were successfully recanalized by passing the ultrasound-guided special cannula, while 150 tubes (75%) were successfully recanalized in group B, using the same tubal catheter through a 2mm microhysteroscope. The cumulative pregnancy rate after the two procedures was not statistically different between two groups. It was 25.9% in group A, while it was 26.3% in group B, after a 12-month period follow-up.

CONCLUSION

UGTR is highly recommended as the first step to manage infertile women due to PTO, as it is easier procedure; however, there is possible to obtain nearly similar results after MHOD.

摘要

背景

就我所知,目前的这项研究是首次比较使用特殊输卵管导管的超声引导下输卵管再通术(UGTR)与在先前诊断为双侧近端输卵管阻塞(PTO)的不孕女性中使用同一输卵管导管进行门诊微型宫腔镜输卵管开口扩张术(MHOD)的妊娠结局。

材料与方法

这项前瞻性研究报告了2010年1月至2013年10月期间在法尤姆的阿拉法医院私立不孕治疗中心和明亚大学医院,200名双侧PTO女性患者在常规子宫输卵管造影(HSG)后作为门诊患者接受治疗的妊娠结局。使用库克导管(一种特殊的输卵管导管)对100名女性(A组)在超声引导下进行输卵管再通术以疏通阻塞的输卵管,另外100名女性(B组)通过2mm微型宫腔镜使用同一库克输卵管导管进行输卵管开口插管以进行MHOD。在手术后进行为期12个月的随访以确定妊娠结局。

结果

两组间PTO再通的数量无显著差异。在A组的200条阻塞输卵管中,140条(70%)通过超声引导下的特殊套管成功再通,而在B组中,使用同一输卵管导管通过2mm微型宫腔镜,150条(75%)成功再通。两种手术方法后的累积妊娠率在两组间无统计学差异。随访12个月后,A组为25.9%,B组为26.3%。

结论

强烈推荐将UGTR作为因PTO导致不孕女性的首选治疗方法,因为它操作更简便;然而,MHOD后也有可能获得相近的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/593c/4793170/9add8ee303c1/Int-J-Fertil-Steril-9-497-g01.jpg

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