一名54岁女性，在接受异基因造血干细胞移植治疗慢性粒细胞白血病后发生供体细胞来源的多发性骨髓瘤。
A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML.
作者信息
Maestas Erika, Jain Shikha, Stiff Patrick
机构信息
Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA.
出版信息
Case Rep Hematol. 2016;2016:6751914. doi: 10.1155/2016/6751914. Epub 2016 Feb 18.
Abstract
Chronic myeloid leukemia is a myeloproliferative disorder that may be treated with hematopoietic stem cell transplantation (HSCT). While posttransplantation relapse of disease resulting from a failure to eradicate the patient's original leukemia could occur, patients may also rarely develop a secondary malignancy or myelodysplastic syndrome (MDS) of donor origin termed donor cell leukemia (DCL). Cases of donor-derived acute myeloid leukemia (AML) or MDS after HSCT or solid tumor transplantation have been published. However, very few cases of donor-derived multiple myeloma (MM) exist. We describe a patient who developed a donor-derived MM following allogeneic HSCT from a sibling donor.
摘要
慢性髓系白血病是一种骨髓增殖性疾病，可通过造血干细胞移植（HSCT）进行治疗。虽然因未能根除患者原有的白血病而导致疾病移植后复发可能会发生，但患者也可能很少会发生源自供体的继发性恶性肿瘤或骨髓增生异常综合征（MDS），即供体细胞白血病（DCL）。HSCT或实体瘤移植后供体来源的急性髓系白血病（AML）或MDS的病例已有报道。然而，供体来源的多发性骨髓瘤（MM）病例非常罕见。我们描述了一名在接受同胞供体的异基因HSCT后发生供体来源MM的患者。
相似文献
1
A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML.
Case Rep Hematol. 2016;2016:6751914. doi: 10.1155/2016/6751914. Epub 2016 Feb 18.
2
Cytomegalovirus Reactivation after Allogeneic Hematopoietic Stem Cell Transplantation is Associated with a Reduced Risk of Relapse in Patients with Acute Myeloid Leukemia Who Survived to Day 100 after Transplantation: The Japan Society for Hematopoietic Cell Transplantation Transplantation-related Complication Working Group.
Biol Blood Marrow Transplant. 2015 Nov;21(11):2008-16. doi: 10.1016/j.bbmt.2015.07.019. Epub 2015 Jul 26.
3
Donor cell leukemia/myelodysplastic syndrome after allogeneic stem cell transplantation: a rare phenomenon with more challenges for hematologists.
Hematology. 2021 Dec;26(1):648-651. doi: 10.1080/16078454.2021.1966224.
4
Current status and development of hematopoietic stem cell transplantation in China: a report from Chinese Hematopoietic Stem Cell Transplantation Register Group.
Chin Med J (Engl). 2011 Aug;124(16):2548-55.
5
Donor cell-derived acute promyelocytic leukemia after allogeneic hematopoietic stem cell transplantation.
Eur J Haematol. 2018 Oct;101(4):570-574. doi: 10.1111/ejh.13143. Epub 2018 Sep 3.
6
HLA-Matched Sibling versus Unrelated versus Haploidentical Related Donor Allogeneic Hematopoietic Stem Cell Transplantation for Patients Aged Over 60 Years with Acute Myeloid Leukemia: A Single-Center Donor Comparison.
Biol Blood Marrow Transplant. 2018 Jul;24(7):1449-1454. doi: 10.1016/j.bbmt.2018.02.002. Epub 2018 Feb 12.
7
Influence of donor age in allogeneic stem cell transplant outcome in acute myeloid leukemia and myelodisplastic syndrome.
Leuk Res. 2015 Aug;39(8):828-34. doi: 10.1016/j.leukres.2015.05.003. Epub 2015 May 14.
8
Treatment of acute myeloid leukemia or myelodysplastic syndrome relapse after allogeneic stem cell transplantation with azacitidine and donor lymphocyte infusions--a retrospective multicenter analysis from the German Cooperative Transplant Study Group.
Biol Blood Marrow Transplant. 2015 Apr;21(4):653-60. doi: 10.1016/j.bbmt.2014.12.016. Epub 2014 Dec 23.
9
Donor Killer Immunoglobulin-Like Receptor Profile Bx1 Imparts a Negative Effect and Centromeric B-Specific Gene Motifs Render a Positive Effect on Standard-Risk Acute Myeloid Leukemia/Myelodysplastic Syndrome Patient Survival after Unrelated Donor Hematopoietic Stem Cell Transplantation.
Biol Blood Marrow Transplant. 2016 Feb;22(2):232-239. doi: 10.1016/j.bbmt.2015.09.007. Epub 2015 Sep 11.
10
[Hematopoietic stem cell transplantation for patients with chronic myelogenous leukemia].
Ai Zheng. 2004 Apr;23(4):426-9.
引用本文的文献
1
Donor-Derived Smoldering Multiple Myeloma following a Hematopoietic Cell Transplantation for AML.
Case Rep Hematol. 2017;2017:3728429. doi: 10.1155/2017/3728429. Epub 2017 Feb 20.
2
Tissue-based chimerism analysis enhances detection of donor-derived neoplasia in allogeneic stem cell transplant patients.
Bone Marrow Transplant. 2017 Apr;52(4):634-637. doi: 10.1038/bmt.2016.332. Epub 2016 Dec 19.
3
National Institutes of Health Hematopoietic Cell Transplantation Late Effects Initiative: The Subsequent Neoplasms Working Group Report.
Biol Blood Marrow Transplant. 2017 Mar;23(3):367-378. doi: 10.1016/j.bbmt.2016.09.005. Epub 2016 Sep 12.
本文引用的文献
1
Donor cell myeloid sarcoma.
Case Rep Hematol. 2014;2014:153989. doi: 10.1155/2014/153989. Epub 2014 Apr 14.
2
A donor cornea with metastatic cells from a cutaneous malignant melanoma.
Cornea. 2013 Dec;32(12):1613-6. doi: 10.1097/ICO.0b013e31829de477.
3
Plasmacytic post-transplant lymphoproliferative disorder: a case series of nine patients.
Transpl Int. 2013 Jun;26(6):616-22. doi: 10.1111/tri.12091. Epub 2013 Mar 28.
4
Donor cell-derived leukemias/myelodysplastic neoplasms in allogeneic hematopoietic stem cell transplant recipients: a clinicopathologic study of 10 cases and a comprehensive review of the literature.
Am J Clin Pathol. 2011 Apr;135(4):525-40. doi: 10.1309/AJCPPJUQ9DNR1GHP.
5
Donor cell origin of multiple myeloma occurring after allogeneic haematopoietic stem cell transplantation in a patient with refractory anaemia with ring sideroblast.
J Clin Pathol. 2011 Mar;64(3):265-8. doi: 10.1136/jcp.2010.084731. Epub 2010 Dec 22.
6
Donor cell leukemia: a review.
Biol Blood Marrow Transplant. 2011 Jun;17(6):771-89. doi: 10.1016/j.bbmt.2010.10.010. Epub 2010 Oct 15.
7
Cost of paid transplantation abroad: possible donor-origin early multiple myeloma in a renal transplant recipient treated using bortezomib.
Transplant Proc. 2010 Sep;42(7):2813-5. doi: 10.1016/j.transproceed.2010.05.164.
8
Chronic myeloid leukaemia.
Lancet. 2007 Jul 28;370(9584):342-50. doi: 10.1016/S0140-6736(07)61165-9.
9
A solid tumor of donor cell-origin after allogeneic peripheral blood stem cell transplantation.
Am J Transplant. 2006 Dec;6(12):3042-3. doi: 10.1111/j.1600-6143.2006.01581.x.
10
Postrenal transplant non-EBV multiple myeloma of donor origin.
Am J Transplant. 2006 Feb;6(2):419-22. doi: 10.1111/j.1600-6143.2005.01170.x.
Zotero 插件