Division of Vascular & Endovascular Surgery, Brigham & Women's Hospital, Boston, Mass.
Center for Surgery and Public Health, Brigham & Women's Hospital, Boston, Mass.
J Vasc Surg Venous Lymphat Disord. 2015 Jul;3(3):290-4. doi: 10.1016/j.jvsv.2014.09.010. Epub 2014 Dec 6.
Surgical treatment of acute axillosubclavian vein thrombosis from venous thoracic outlet syndrome (VTOS) traditionally involves first rib resection and scalenectomy (FRRS) followed by interval venography and balloon angioplasty. This approach can lead to an extended need for anticoagulation and a separate anesthesia session. We present outcomes for FRRS with concurrent venography.
Retrospective chart review was performed for consecutive patients undergoing FRRS with concurrent venography for VTOS from February 2007 to April 2014. Venography was performed immediately after FRRS with the arm in neutral and provocative positions. The primary outcomes of this study were primary and primary-assisted patency. Secondary outcomes included whether concurrent venography resulted in modification of the procedure, postoperative anticoagulation use, and postoperative complications.
Thirty patients underwent first rib resection with venography with a mean follow-up time of 24.4 months. The mean age was 29.5 years (range, 17-52 years), and 17 (56.7%) were female. All were maintained on anticoagulation before the procedure. Concurrent venography resulted in modification of the procedure in 28 patients (93.3%). Of these, 27 patients (96.4%) underwent balloon angioplasty and two patients (7.1%) underwent further rib resection. Twenty patients (66.7%) were discharged after the procedure with no anticoagulation. For those receiving postoperative anticoagulation for persistent minor thrombus, median time for anticoagulation duration was 5.0 months (range, 0.8 and 16.7 months). Two patients (6.7%) had postoperative bleeding requiring thoracentesis or video-assisted thoracoscopic evacuation of hemothorax. One patient (3.3%) suffered rethrombosis and was successfully lysed open, resulting in a 2-year subclavian vein (SCV) primary patency of 96.7% and primary-assisted patency of 100%. No patients required reoperation for VTOS, and all reported improvements in symptoms. Three patients (10.0%) later underwent prophylactic first rib resection on the contralateral side for symptoms and SCV stenosis.
FRRS with concurrent venography is a safe procedure for VTOS that allows effective intraoperative modification of the surgical plan, resulting in excellent patency of the SCV, early cessation of anticoagulation, and durable relief of symptoms.
传统上,治疗急性锁骨下静脉血栓形成的手术方法包括切除第一肋骨和前斜角肌切除术(FRRS),然后进行静脉造影和球囊血管成形术。这种方法可能需要延长抗凝治疗时间和进行单独的麻醉。我们介绍了 FRRS 联合静脉造影的治疗效果。
回顾性分析了 2007 年 2 月至 2014 年 4 月期间因静脉胸廓出口综合征(VTOS)行 FRRS 联合静脉造影的连续患者的病历。在 FRRS 后,手臂保持中立和激发位置,立即进行静脉造影。本研究的主要结果是原发性和原发性辅助通畅率。次要结果包括静脉造影是否导致手术方式改变、术后抗凝使用和术后并发症。
30 例患者行第一肋骨切除术联合静脉造影,平均随访时间为 24.4 个月。平均年龄为 29.5 岁(范围 17-52 岁),17 例(56.7%)为女性。所有患者在手术前均接受抗凝治疗。28 例(93.3%)患者因静脉造影而改变手术方式。其中 27 例(96.4%)患者行球囊血管成形术,2 例(7.1%)患者行进一步肋骨切除术。20 例(66.7%)患者术后无需抗凝即可出院。对于那些因持续性小血栓而接受术后抗凝的患者,抗凝时间中位数为 5.0 个月(范围 0.8-16.7 个月)。2 例(6.7%)患者术后出现出血,需行胸腔穿刺或电视辅助胸腔镜清除血胸。1 例(3.3%)患者再次发生血栓形成,并成功溶栓,导致 2 年锁骨下静脉(SCV)原发性通畅率为 96.7%,原发性辅助通畅率为 100%。无患者因 VTOS 再次手术,所有患者症状均改善。3 例(10.0%)患者因症状和 SCV 狭窄在对侧行预防性第一肋骨切除术。
FRRS 联合静脉造影是治疗 VTOS 的一种安全方法,可在术中有效修改手术方案,使 SCV 通畅率高、抗凝治疗时间早、症状持久缓解。