Chemical Biology Research Group, RIKEN CSRS, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan.
Nat Prod Rep. 2016 May 4;33(5):621-5. doi: 10.1039/c5np00106d.
Covering: up to the end of 2015.Many useful compounds from natural products have been discovered through phenotype-based screening. However, the target identification process for compounds is laborious and time-consuming. With the development of new equipment and methodologies for biological analyses, a variety of profiling methods that utilize large sets of experimental data have been established. Here, we highlight the utility of our identification approaches, MorphoBase and ChemProteoBase.
截至 2015 年底。通过基于表型的筛选,已经发现了许多来自天然产物的有用化合物。然而,化合物的靶标鉴定过程既费力又耗时。随着生物分析新设备和新方法的发展,已经建立了各种利用大量实验数据的剖析方法。在这里,我们强调了我们的鉴定方法 MorphoBase 和 ChemProteoBase 的实用性。