Opendak Maya, Briones Brandy A, Gould Elizabeth
Department of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Department of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Front Neuroendocrinol. 2016 Apr;41:71-86. doi: 10.1016/j.yfrne.2016.02.002. Epub 2016 Mar 17.
A variety of experiences have been shown to affect the production of neurons in the adult hippocampus. These effects may be mediated by experience-driven hormonal changes, which, in turn, interact with factors such as sex, age and life history to alter brain plasticity. Although the effects of physical experience and stress have been extensively characterized, various types of social experience across the lifespan trigger profound neuroendocrine changes in parallel with changes in adult neurogenesis. This review article focuses on the influence of specific social experiences on adult neurogenesis in the dentate gyrus and the potential role of hormones in these effects.
多种经历已被证明会影响成年海马体中神经元的产生。这些影响可能由经验驱动的激素变化介导，而激素变化又会与性别、年龄和生活史等因素相互作用，从而改变大脑可塑性。尽管身体经验和压力的影响已得到广泛研究，但一生中各种类型的社会经验会引发深刻的神经内分泌变化，同时伴随着成年神经发生的变化。这篇综述文章重点关注特定社会经验对齿状回成年神经发生的影响以及激素在这些影响中的潜在作用。
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